Sepsis is a potent activator of the hemostatic and complement systems. While local
activation of these proteolytic cascades contributes to the host defense, their uncontrolled …

Fibrogenesis involves a dynamic interplay between factors that promote the biosynthesis
and deposition of extracellular matrix along with pathways that degrade the extracellular …

Acute respiratory distress syndrome (ARDS) is a severe clinical disorder characterized by its
acute onset, diffuse alveolar damage, intractable hypoxemia, and non-cardiogenic …

Sepsis-induced acute respiratory distress syndrome (ARDS) has high morbidity and
mortality, and it has three major pathogeneses, namely alveolar–capillary barrier …

Extracellular histones are mediators of tissue injury and organ dysfunction; therefore they
constitute potential therapeutic targets in sepsis, inflammation, and thrombosis. Histone …

Background Bacterial infection is one of the most common causes of sepsis, with acute lung
injury (ALI) being a related complication. Pterostilbene (PTS) is extracted from blueberries …

Acute lung injury (ALI) is an inflammatory lung disease that is caused by bacterial infection.
Lipopolysaccharide (LPS), a prototype pathogen-associated molecular pattern (PAMP) from …

Pulmonary vascular endothelial dysfunction is a key pathogenic mechanism in acute
respiratory distress syndrome (ARDS), resulting in fibrosis in lung tissues, including in the …

Ophiocordyceps sinensis is a fungus with medicinal value in treating lung diseases, but no
study has reported how to prevent acute lung injury using this fungus. The mice were …

Sepsis is still the leading cause of death as a result of infection. Metabolic disorder plays a
vital role in sepsis progression. Glycolysis intensification is the most characteristic feature of …