Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …

Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

Oocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain
mature oocytes following culture of immature cumulus–oocyte complexes collected from …

In vitro fertilization (IVF) is currently one of the most effective methods of infertility treatment.
An alternative to commonly used ovarian hyperstimulation can become extracorporeal …

BACKGROUND Knowledge of the proteomic composition of the gametes is essential to
understand reproductive functions. Most of the sperm proteins are related to …

Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

Germ cells are physically coupled to somatic support cells of the gonad during
differentiation, but this coupling must be disrupted when they are mature, freeing them to …

Oocyte in vitro maturation (IVM) is an assisted reproductive technology with a long and
sometimes checked history. It is a minimally invasive technique involving the deliberate …