Background Recruitment and retention to surgical trials has previously been reported to be
problematic, resulting in research waste. Surgery often results in wounds, meaning these …

Background Effective and efficient conduct of randomised controlled trials (RCTs) ensures
accurate, timely results and prevents research waste. There is however limited evidence …

Introduction The PROMETHEUS programme (PROMoting THE USE of SWATs) was funded
by the UK Medical Research Council (MRC) and Clinical Trials Unit (CTU) infrastructure …

Aim PROMoting THE USE of Studies Within A Trial (PROMETHEUS) aimed to improve the
evidence base for recruiting and retaining participants in Randomised Controlled Trials …

Background Difficulties recruiting to clinical trials are well-documented. Strategies to engage
staff from the clinical site where recruitment takes place may be helpful in increasing …

BACKGROUND Randomised controlled trials ('trials') are susceptible to poor participant
recruitment and retention. Studies Within A Trial are the strongest methods for testing the …

Background Suboptimal or slow recruitment affects 30–50% of trials. Education and training
of trial recruiters has been identified as one strategy for potentially boosting recruitment to …

Objectives Recruiting to randomised trials is often challenging particularly when the
intervention arms are markedly different. The Mesothelioma and Radical Surgery 2 …

Background Randomised trials play a vital role in underpinning evidence-based care.
However, trials involving adults with impaired capacity to consent raise a number of ethical …

Background: Herpes zoster (shingles) is normally diagnosed clinically. Timely diagnosis is
important so antiviral treatment can be started soon after rash onset. Aim: To assess whether …