The endoplasmic reticulum (ER) comprises a network of tubules and vesicles that
constitutes the largest organelle of the eukaryotic cell. Being the location where most …

Degenerative cervical myelopathy (DCM) is the most prevalent cause of spinal cord
dysfunction in the aging population. Significant neurological deficits may result from a …

Endoplasmic reticulum (ER) and mitochondrial function have both been shown to be critical
events in neurodegenerative diseases. The ER mediates protein folding, maturation, sorting …

Varied pathogenetic elements have been touched upon the liver fibrosis, including
inflammatory, stress, apoptosis and unfolded proteins aggregation. Magnesium …

Classic Galactosemia is an autosomal recessive disorder caused by deleterious mutations
in the GALT gene, which encodes galactose-1 phosphate uridylyltransferase enzyme …

Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or
mechanical contusions (eg, traumatic brain injury, TBI) comprise a diverse group of …

Limb girdle muscular dystrophy type R1 disease is a progressive disease that is caused by
mutations in the CAPN3 gene and involves the extremity muscles of the hip and shoulder …

Following a central nervous system (CNS) injury, restoration of the blood‐brain barrier (BBB)
integrity is essential for recovering homeostasis. When this process is delayed or impeded …

Traumatic brain injury (TBI) is an incredibly heterogenous pathology, yet many of the current
mechanisms under exploration involve a common phenotype, traumatic axonal injury (TAI) …

Lung cancer is the leading cause of cancer related deaths worldwide and is the second
most commonly diagnosed cancer among men and women. Due to advances in genetic …