Manganese: recent advances in understanding its transport and neurotoxicity

M Aschner, TR Guilarte, JS Schneider… - Toxicology and applied …, 2007 - Elsevier
The present review is based on presentations from the meeting of the Society of Toxicology
in San Diego, CA (March 2006). It addresses recent developments in the understanding of …

Anemia as a risk factor for tuberculosis: a systematic review and meta-analysis

Y Gelaw, Z Getaneh, M Melku - Environmental Health and Preventive …, 2021 - Springer
Background Tuberculosis is a major public health problem caused by Mycobacterium
tuberculosis, occurring predominantly in population with low socioeconomic status. It is the …

[HTML][HTML] Iron metabolism and the innate immune response to infection

EE Johnson, M Wessling-Resnick - Microbes and infection, 2012 - Elsevier
Host antimicrobial mechanisms reduce iron availability to pathogens. Iron proteins
influencing the innate immune response include hepcidin, lactoferrin, siderocalin …

[HTML][HTML] Iron supplementation in early childhood: health benefits and risks

LL Iannotti, JM Tielsch, MM Black, RE Black - The American journal of …, 2006 - Elsevier
The prevalence of iron deficiency among infants and young children living in developing
countries is high. Because of its chemical properties—namely, its oxidative potential—iron …

[HTML][HTML] Iron Deficiency and Anemia Predict Mortality in Patients with Tuberculosis3

S Isanaka, F Mugusi, W Urassa, WC Willett… - The Journal of …, 2012 - Elsevier
Many studies have documented a high prevalence of anemia among tuberculosis (TB)
patients and anemia at TB diagnosis has been associated with an increased risk of death …

Iron homeostasis in Mycobacterium tuberculosis: mechanistic insights into siderophore-mediated iron uptake

M Sritharan - Journal of bacteriology, 2016 - Am Soc Microbiol
Mycobacterium tuberculosis requires iron for normal growth but faces a limitation of the
metal ion due to its low solubility at biological pH and the withholding of iron by the …

The effect of the host's iron status on tuberculosis

JR Boelaert, SJ Vandecasteele… - The Journal of …, 2007 - academic.oup.com
Several lines of evidence have suggested that iron is critical for Mycobacterium tuberculosis
growth in macrophages. Macrophage iron loading in patients with African iron overload …

[HTML][HTML] Free-living amoebae, a training field for macrophage resistance of mycobacteria

IB Salah, E Ghigo, M Drancourt - Clinical Microbiology and Infection, 2009 - Elsevier
Mycobacterium species evolved from an environmental recent common ancestor by
reductive evolution and lateral gene transfer. Strategies selected through evolution and …

Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies

RJ Basaraba - Tuberculosis, 2008 - Elsevier
The use of laboratory animals is critical to the discovery and in vivo pre-clinical testing of
new drugs and drug combinations for use in humans. M. tuberculosis infection of mice, rats …

Host-pathogen interaction as a novel target for host-directed therapies in tuberculosis

R Abreu, P Giri, F Quinn - Frontiers in immunology, 2020 - frontiersin.org
Tuberculosis (TB) has been a transmittable human disease for many thousands of years,
and M. tuberculosis is again the number one cause of death worldwide due to a single …