Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of GT mispairs in nuclear extracts from human cells.
K Wiebauer, J Jiricny - … of the National Academy of Sciences, 1990 - National Acad Sciences
To avoid the mutagenic effect of spontaneous hydrolytic deamination of 5-methylcytosine,
GT mispairs, arising in DNA as a result of this process, should always be corrected to GC …
GT mispairs, arising in DNA as a result of this process, should always be corrected to GC …
Eukaryotic DNA polymerases
TSF Wang - Eukaryotic DNA Replication, 1999 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p> DNA polymerases are the fundamental
enzymes that synthesize cellular DNA to produce two identical daughter chromosomes …
enzymes that synthesize cellular DNA to produce two identical daughter chromosomes …
Structures of ternary complexes of rat DNA polymerase β, a DNA template-primer, and ddCTP
H Pelletier, MR Sawaya, A Kumar, SH Wilson, J Kraut - Science, 1994 - science.org
Two ternary complexes of rat DNA polymerase β (pol β), a DNA template-primer, and
dideoxycytidine triphosphate (ddCTP) have been determined at 2.9 Å and 3.6 Å resolution …
dideoxycytidine triphosphate (ddCTP) have been determined at 2.9 Å and 3.6 Å resolution …
Compilation and alignment of DNA polymerase sequences.
J Ito, DK Braithwaite - Nucleic acids research, 1991 - ncbi.nlm.nih.gov
E. coli DNA polymerase IH is a multisubunit enzyme encoded by various dna genes (55); the
DNA polymerizing a-subunit encoded by thepolC (dnaE) gene (56) and the 3' …
DNA polymerizing a-subunit encoded by thepolC (dnaE) gene (56) and the 3' …
Unit-length line-1 transcripts in human teratocarcinoma cells
J Skowronski, TG Fanning… - Molecular and cellular …, 1988 - Taylor & Francis
We have characterized the approximately 6.5-kilobase cytoplasmic poly (A)+ Line-1 (L1)
RNA present in a human teratocarcinoma cell line, NTera2D1, by primer extension and by …
RNA present in a human teratocarcinoma cell line, NTera2D1, by primer extension and by …
Crystal Structures of Human DNA Polymerase β Complexed with DNA: Implications for Catalytic Mechanism, Processivity, and Fidelity,
H Pelletier, MR Sawaya, W Wolfle, SH Wilson… - Biochemistry, 1996 - ACS Publications
Mammalian DNA polymerase β (pol β) is a small (39 kDa) DNA gap-filling enzyme that
comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. In the …
comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. In the …
Induction by Ionizing Radiation of the gadd45 Gene in Cultured Human Cells: Lack of Mediation by Protein Kinase C
MA Papathanasiou, NCK Kerr, JH Robbins… - … and cellular biology, 1991 - Taylor & Francis
The effect of ionizing radiation on the expression of two DNA-damage-inducible genes,
designated gadd45 and gaddl53 was examined in cultured human cells. These genes have …
designated gadd45 and gaddl53 was examined in cultured human cells. These genes have …
[HTML][HTML] Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain.
A Kumar, SG Widen, KR Williams, P Kedar… - Journal of Biological …, 1990 - Elsevier
Characterization of the domain structure of DNA polymerase beta is reported. Large scale
overproduction of the rat protein in Escherichia coli was achieved, and the purified …
overproduction of the rat protein in Escherichia coli was achieved, and the purified …
DNA polymerase β expression differences in selected human tumors and cell lines
DK Srivastava, I Husain, CL Arteaga… - …, 1999 - academic.oup.com
A long-standing question in cancer biology has been the extent to which DNA repair may be
altered during the process of carcinogenesis. We have shown recently that DNA polymerase …
altered during the process of carcinogenesis. We have shown recently that DNA polymerase …
Lack of sugar discrimination by human Pol µ requires a single glycine residue
JF Ruiz, R Juárez, M García‐Díaz… - Nucleic acids …, 2003 - academic.oup.com
DNA polymerase mu (Pol µ) is a novel family X DNA polymerase that has been suggested to
play a role in micro‐homology mediated joining and repair of double strand breaks. We …
play a role in micro‐homology mediated joining and repair of double strand breaks. We …