Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases

M Herre, J Cedervall, N Mackman… - Physiological …, 2023 - journals.physiology.org
Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

[HTML][HTML] Molecularly self‐fueled nano-penetrator for nonpharmaceutical treatment of thrombosis and ischemic stroke

H Zhang, Z Zhao, S Sun, S Zhang, Y Wang… - Nature …, 2023 - nature.com
Thrombotic cerebro-cardiovascular diseases are the leading causes of disability and death
worldwide. However, current drug therapeutics are compromised by narrow therapeutic …

Embolic stroke of undetermined source: a systematic review and clinical update

RG Hart, L Catanese, KS Perera, G Ntaios, SJ Connolly - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Embolic stroke of undetermined source (ESUS) designates
patients with nonlacunar cryptogenic ischemic strokes in whom embolism is the likely stroke …

Neutrophil extracellular traps in ischemic stroke thrombi

E Laridan, F Denorme, L Desender… - Annals of …, 2017 - Wiley Online Library
Objective Neutrophil extracellular traps (NETs) have been shown to promote thrombus
formation. Little is known about the exact composition of thrombi that cause ischemic stroke …

[HTML][HTML] Neutrophil extracellular traps in arterial and venous thrombosis

E Laridan, K Martinod… - Seminars in thrombosis …, 2019 - thieme-connect.com
Thrombotic complications are still a major health risk worldwide. Our view on the
pathophysiology of thrombosis has significantly changed since the discovery of neutrophil …

Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: a systematic review

W Brinjikji, S Duffy, A Burrows, W Hacke… - Journal of …, 2017 - jnis.bmj.com
Background and purpose Studying the imaging and histopathologic characteristics of
thrombi in ischemic stroke could provide insights into stroke etiology and ideal treatment …

Ischemic stroke: what does the histological composition tell us about the origin of the thrombus?

PB Sporns, U Hanning, W Schwindt, A Velasco… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—The introduction of stent retrievers allows for a complete
extraction and histological analysis of human thrombi. Ischemic stroke is a major health …

[HTML][HTML] Erythrocyte-rich thrombus is associated with reduced number of maneuvers and procedure time in patients with acute ischemic stroke undergoing mechanical …

K Maekawa, M Shibata, H Nakajima… - Cerebrovascular …, 2018 - karger.com
Background: Only few studies have investigated the relationship between the histopathology
of retrieved thrombi and clinical outcomes. This study aimed to evaluate thrombus …

Elaborately engineering a self‐Indicating dual‐drug nanoassembly for site‐specific photothermal‐potentiated thrombus penetration and thrombolysis

Z Zhao, X Zhang, H Zhang, X Shan, M Bai… - Advanced …, 2022 - Wiley Online Library
Thrombotic cardio‐cerebrovascular diseases seriously threaten human health. Currently,
conventional thrombolytic treatments are challenged by the low utilization, inferior thrombus …