Early life adversity and neuropsychiatric disease: differential outcomes and translational relevance of rodent models
RC Waters, E Gould - Frontiers in systems neuroscience, 2022 - frontiersin.org
It is now well-established that early life adversity (ELA) predisposes individuals to develop
several neuropsychiatric conditions, including anxiety disorders, and major depressive …
several neuropsychiatric conditions, including anxiety disorders, and major depressive …
Adolescent Nonpharmacological Interventions for Early-Life Stress and Their Mechanism
Y Li, DD Shi, Z Wang - Behavioural Brain Research, 2023 - Elsevier
Those with a negative experience of psychosocial stress during the early stage of life not
only have a high susceptibility of the psychiatric disorder in all phases of their life span, but …
only have a high susceptibility of the psychiatric disorder in all phases of their life span, but …
Loss of spines in the prelimbic cortex is detrimental to working memory in mice with early-life adversity
L Xu, Y Liu, J Long, X He, F Xie, Q Yin, M Chen… - Molecular …, 2023 - nature.com
Adverse experiences in early life can shape neuronal structures and synaptic function in
multiple brain regions, leading to deficits of distinct cognitive functions later in life. Focusing …
multiple brain regions, leading to deficits of distinct cognitive functions later in life. Focusing …
A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences
Exposure to early-life adversity (ELA) is associated with several neuropsychiatric conditions,
including major depressive disorder, yet causality is difficult to establish in humans. Recent …
including major depressive disorder, yet causality is difficult to establish in humans. Recent …
Early resource scarcity alters motivation for natural rewards in a sex-and reinforcer-dependent manner
AV Williams, J Flowers, KS Coates, A Ingram… - …, 2022 - Springer
Rationale Early life adversity impacts reward-related behaviors, including reward seeking for
drugs of abuse. However, the effects of early stress on natural rewards, such as food and …
drugs of abuse. However, the effects of early stress on natural rewards, such as food and …
Sex-specific behavioral outcomes of early-life adversity and emerging microglia-dependent mechanisms
MM Garvin, JL Bolton - Frontiers in behavioral neuroscience, 2022 - frontiersin.org
Early-life adversity (ELA) is known to alter brain circuit maturation as well as increase
vulnerability to cognitive and emotional disorders. However, the importance of examining …
vulnerability to cognitive and emotional disorders. However, the importance of examining …
[HTML][HTML] Sex differences in addiction-relevant behavioral outcomes in rodents following early life stress
M Rincón-Cortés - Addiction neuroscience, 2023 - Elsevier
In humans, exposure to early life stress (ELS) is an established risk factor for the
development of substance use disorders (SUDs) during later life. Similarly, rodents exposed …
development of substance use disorders (SUDs) during later life. Similarly, rodents exposed …
Early adversity changes the economic conditions of mouse structural brain network organization
Early adversity can change educational, cognitive, and mental health outcomes. However,
the neural processes through which early adversity exerts these effects remain largely …
the neural processes through which early adversity exerts these effects remain largely …
Early adversity changes the economic conditions of structural brain network organisation
Early adversity can change educational, cognitive, and mental health outcomes. However,
the neural processes through which early adversity exerts these effects remain largely …
the neural processes through which early adversity exerts these effects remain largely …
History of “serve and return” and a synthesis of the literature on its impacts on children's health and development
J Komanchuk, N Letourneau… - Issues in Mental …, 2023 - Taylor & Francis
Parent/caregiver sensitivity and responsiveness are important for children's health and
development. The “serve and return” metaphor was created to help providers and caregivers …
development. The “serve and return” metaphor was created to help providers and caregivers …