Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

In mammals, the circadian clocks network (central and peripheral oscillators) controls
circadian rhythms and orchestrates the expression of a range of downstream genes …

In 2020, the world gained dramatic experience of the development of the 2019 coronavirus
disease pandemic (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV …

Glucocorticoid hormones are a powerful mammalian systemic hormonal signal that exerts
regulatory effects on almost every cell and system of the body. Glucocorticoids act in a …

Although it has been suggested that glaucoma is associated with circadian misalignment,
sleep disorder, anxiety, and depression, these comorbid conditions have not received much …

It has been suggested for some time that circadian rhythm abnormalities underlie the
development of multiple psychiatric disorders. However, it is unclear how disruptions in …

Aims: Circadian clock genes are involved in the development of drug-induced behaviors
and regulate neurotransmission pathways in addiction. Our aim was to study whether …

Synthetic drug-like molecules that directly modulate the activity of key clock proteins offer the
potential to directly modulate the endogenous circadian rhythm and treat diseases …

A plethora of physiological processes show stable and synchronized daily oscillations that
are either driven or modulated by biological clocks. A circadian pacemaker located in the …