Gallic acid: A versatile antioxidant with promising therapeutic and industrial applications
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the
leading cause of several degenerative diseases such as cancer, atherosclerosis …
leading cause of several degenerative diseases such as cancer, atherosclerosis …
p‐Coumaric acid and its conjugates: dietary sources, pharmacokinetic properties and biological activities
K Pei, J Ou, J Huang, S Ou - Journal of the Science of Food and …, 2016 - Wiley Online Library
Abstract p‐Coumaric acid (4‐hydroxycinnamic acid) is a phenolic acid that has low toxicity in
mice (LD50= 2850 mg kg− 1 body weight), serves as a precursor of other phenolic …
mice (LD50= 2850 mg kg− 1 body weight), serves as a precursor of other phenolic …
Computational methods in drug discovery
Computer-aided drug discovery/design methods have played a major role in the
development of therapeutically important small molecules for over three decades. These …
development of therapeutically important small molecules for over three decades. These …
Plant‐Based Synthesis of Zinc Oxide Nanoparticles (ZnO‐NPs) Using Aqueous Leaf Extract of Aquilegia pubiflora: Their Antiproliferative Activity against HepG2 Cells Inducing …
The anti‐cancer, anti‐aging, anti‐inflammatory, antioxidant, and anti‐diabetic effects of zinc
oxide nanoparticles (ZnO‐NPs) produced from aqueous leaf extract of Aquilegia pubiflora …
oxide nanoparticles (ZnO‐NPs) produced from aqueous leaf extract of Aquilegia pubiflora …
Melanins and melanogenesis: from pigment cells to human health and technological applications
During the past decade, melanins and melanogenesis have attracted growing interest for a
broad range of biomedical and technological applications. The burst of polydopamine …
broad range of biomedical and technological applications. The burst of polydopamine …
Inhibitors of melanogenesis: an updated review
T Pillaiyar, V Namasivayam, M Manickam… - Journal of medicinal …, 2018 - ACS Publications
Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …
Flavones: An important scaffold for medicinal chemistry
Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl
cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular …
cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular …
[HTML][HTML] Natural skin‑whitening compounds for the treatment of melanogenesis
W Qian, W Liu, D Zhu, Y Cao… - Experimental and …, 2020 - spandidos-publications.com
Melanogenesis is the process for the production of melanin, which is the primary cause of
human skin pigmentation. Skin‑whitening agents are commercially available for those who …
human skin pigmentation. Skin‑whitening agents are commercially available for those who …
Recent advances in triazoles as tyrosinase inhibitors
A Mermer, S Demirci - European Journal of Medicinal Chemistry, 2023 - Elsevier
The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …
significant position in melanogenesis, plays an important role in undesirable browning of …
[HTML][HTML] An updated review of tyrosinase inhibitors
TS Chang - International journal of molecular sciences, 2009 - mdpi.com
Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which
catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic …
catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic …