Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review

N Esplen, MS Mendonca… - Physics in Medicine & …, 2020 - iopscience.iop.org
Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

FLASH radiotherapy with photon beams

P Montay‐Gruel, S Corde, JA Laissue… - Medical …, 2022 - Wiley Online Library
Ultra‐high‐dose rate “FLASH” radiotherapy (FLASH‐RT) has been shown to drastically
reduce normal tissue toxicities while being as efficacious as conventional dose rate …

Comparative toxicity of synchrotron and conventional radiation therapy based on total and partial body irradiation in a murine model

LML Smyth, JF Donoghue, JA Ventura, J Livingstone… - Scientific reports, 2018 - nature.com
Synchrotron radiation can facilitate novel radiation therapy modalities such as microbeam
radiation therapy (MRT) and high dose-rate synchrotron broad-beam radiation therapy …

Technical advances in x-ray microbeam radiation therapy

S Bartzsch, S Corde, JC Crosbie, L Day… - Physics in Medicine …, 2020 - iopscience.iop.org
In the last 25 years microbeam radiation therapy (MRT) has emerged as a promising
alternative to conventional radiation therapy at large, third generation synchrotrons. In MRT …

Animal models in microbeam radiation therapy: a scoping review

C Fernandez-Palomo, J Fazzari, V Trappetti, L Smyth… - Cancers, 2020 - mdpi.com
Background: Microbeam Radiation Therapy (MRT) is an innovative approach in radiation
oncology where a collimator subdivides the homogeneous radiation field into an array of co …

[HTML][HTML] Synchrotron microbeam radiation therapy for the treatment of lung carcinoma: a preclinical study

V Trappetti, C Fernandez-Palomo, L Smyth… - International Journal of …, 2021 - Elsevier
Purpose In the last three decades, Synchrotron Microbeam Radiation Therapy (S-MRT) has
been shown to achieve both good tumour control and normal tissue sparing in a range of …

A study on the suitability of the PTW microDiamond detector for kilovoltage x-ray beam dosimetry

J Damodar, D Odgers, D Pope, R Hill - Applied Radiation and Isotopes, 2018 - Elsevier
Kilovoltage x-ray beams are widely used in treating skin cancers and in biological
irradiators. In this work, we have evaluated four dosimeters (ionization chambers and solid …

X-ray phase-contrast computed tomography for soft tissue imaging at the imaging and medical beamline (IMBL) of the Australian synchrotron

BD Arhatari, AW Stevenson, B Abbey, YI Nesterets… - Applied Sciences, 2021 - mdpi.com
The Imaging and Medical Beamline (IMBL) is a superconducting multipole wiggler-based
beamline at the 3 GeV Australian Synchrotron operated by the Australian Nuclear Science …

A commercial treatment planning system with a hybrid dose calculation algorithm for synchrotron radiotherapy trials

LRJ Day, M Donzelli, P Pellicioli… - Physics in Medicine …, 2021 - iopscience.iop.org
Abstract Synchrotron Radiotherapy (SyncRT) is a preclinical radiation treatment which
delivers synchrotron x-rays to cancer targets. SyncRT allows for novel treatments such as …

First experimental measurement of the effect of cardio‐synchronous brain motion on the dose distribution during microbeam radiation therapy

M Duncan, M Donzelli, P Pellicioli… - Medical …, 2020 - Wiley Online Library
Purpose Microbeam radiation therapy (MRT) is an emerging radiation oncology modality
ideal for treating inoperable brain tumors. MRT employs quasi‐parallel beams of low …