More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …

This Review illustrates the evaluation of permeability of lipid membranes from molecular
dynamics (MD) simulation primarily using water and oxygen as examples. Membrane …

Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

In this study, we synthesized thermo-responsive chitosan (TCTS) hydrogels, and loaded with
different concentrations of antimicrobial peptide (AMP)(0, 4, 8 and 16 μg· ml− 1) to fabricate …

Antimicrobial peptides (AMPs) are produced by several organisms as their first line of
defense. Constituted by amino acids, they may present different mechanisms of action. The …

Concepts of solid-state NMR spectroscopy and applications to fluid membranes are
reviewed in this paper. Membrane lipids with 2H-labeled acyl chains or polar head groups …

Piscidins are histidine-enriched antimicrobial peptides that interact with lipid bilayers as
amphipathic α-helices. Their activity at acidic and basic pH in vivo makes them promising …

Membrane active peptides are known to porate lipid bilayers, but their exact
permeabilization mechanism and the structure of the nanoaggregates they form in …

How can highly charged, cationic antimicrobial peptides (AMPs) translocate across
hydrophobic lipid bilayers despite the prohibitive energetic penalty to do so? A common …