Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Challenge with specific microbial stimuli induces long lasting epigenetic changes in innate
immune cells that result in their enhanced response to a second challenge by the same or …

Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …

Trained immunity is a de facto memory for innate immune responses, leading to long-term
functional reprogramming of innate immune cells. In physiological conditions, trained …

MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients
against recurrent respiratory infections, including those of viral etiology. However, its …

Background Recurrent urinary tract infections (UTIs), which consist of three or more
episodes in 1 year or two or more infections in 6 months, affect 5% to 10% of women …

Rationale: Recurrent wheezing in children represents a severe public health concern.
Wheezing attacks (WA), mainly associated with viral infections, lack effective preventive …

In light of an escalating prevalence of allergic disorders, it is crucial to fully comprehend their
pathophysiology and etiology. Such knowledge would play a pivotal role in the search for …

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common form of
childhood cancer. Chemotherapy is associated with life-long health sequelae and fails in∼ …

COVID-19-specific vaccines are efficient prophylactic weapons against SARS-CoV-2 virus.
However, boosting innate responses may represent an innovative way to immediately fight …