Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

This review summarises current understanding of how bone is sculpted through adaptive
processes, designed to meet the mechanical challenges it faces in everyday life and athletic …

Bone defects characterized by limited regenerative properties are considered a priority in
surgical practice, as they are associated with reduced quality of life and high costs. In bone …

Skin injury is a common occurrence and mechanical forces are known to significantly impact
the biological processes of skin regeneration and wound healing. Immediately following the …

Spatiotemporal Immune disorder is a key factor leading to the failure of bone tissue healing.
It is of vital importance to accurately suppress excessive peak immune response within 24 …

Pathological scarring imposes a major clinical and social burden worldwide. Human
cutaneous wounds are responsive to mechanical forces and convert mechanical cues to …

Bone and cartilage regeneration is an area of tremendous interest and need in health care.
Tissue engineering is a potential strategy for repairing and regenerating bone and cartilage …

Bone is a tissue with constant remodeling, where osteoblasts form and osteoclasts degrade
bone. Both cell types are highly specialized in their function and both form from precursors …

Mechanical stress maintains tissue homeostasis by regulating many cellular functions
including cell proliferation, differentiation, and inflammation and immune responses. In …

Objective To evaluate the dose–response relationship of exercise loading in the cartilage-
subchondral bone (SB) unit in surgically-induced post-traumatic osteoarthritis (PTOA) of the …