The microbiome of the upper respiratory tract in health and disease

C Kumpitsch, K Koskinen, V Schöpf… - BMC biology, 2019 - Springer
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

[HTML][HTML] The microbiota of the respiratory tract: gatekeeper to respiratory health

WH Man, WAA de Steenhuijsen Piters… - Nature Reviews …, 2017 - nature.com
The respiratory tract is a complex organ system that is responsible for the exchange of
oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung …

Understanding respiratory microbiome–immune system interactions in health and disease

SK Di Simone, I Rudloff, CA Nold-Petry… - Science translational …, 2023 - science.org
Interactions between the developing microbiome and maturing immune system in early life
are critical for establishment of a homeostasis beneficial to both host and commensals. The …

Immunological effects of human milk oligosaccharides

V Triantis, L Bode, RJJ Van Neerven - Frontiers in pediatrics, 2018 - frontiersin.org
Human milk oligosaccharides (HMOs) comprise a group of structurally complex,
unconjugated glycans that are highly abundant in human milk. HMOs are minimally digested …

Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children

G Biesbroek, E Tsivtsivadze, EAM Sanders… - American journal of …, 2014 - atsjournals.org
Rationale: Many bacterial pathogens causing respiratory infections in children are common
residents of the respiratory tract. Insight into bacterial colonization patterns and microbiota …

Maturation of the infant respiratory microbiota, environmental drivers, and health consequences. A prospective cohort study

AATM Bosch, WAAS Piters, MA van Houten… - American journal of …, 2017 - atsjournals.org
Rationale: Perinatal and postnatal influences are presumed important drivers of the early-life
respiratory microbiota composition. We hypothesized that the respiratory microbiota …

Breastfeeding and childhood acute otitis media: a systematic review and meta‐analysis

G Bowatte, R Tham, KJ Allen, DJ Tan, MXZ Lau… - Acta …, 2015 - Wiley Online Library
Aim To synthesise the evidence on the association between duration and exclusivity of
breastfeeding and the risk of acute otitis media (AOM). Methods Systematic review and meta …

Breast milk: A source of functional compounds with potential application in nutrition and therapy

C Sánchez, L Franco, P Regal, A Lamas, A Cepeda… - Nutrients, 2021 - mdpi.com
Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in
its different stages of growth up to six months after birth. In addition, breastfeeding benefits …

Bacterial and viral respiratory tract microbiota and host characteristics in children with lower respiratory tract infections: a matched case-control study

WH Man, MA van Houten, ME Mérelle… - The Lancet …, 2019 - thelancet.com
Background Lower respiratory tract infections (LRTIs) are a leading cause of childhood
morbidity and mortality. Potentially pathogenic organisms are present in the respiratory tract …

The role of the local microbial ecosystem in respiratory health and disease

WAA de Steenhuijsen Piters… - … Transactions of the …, 2015 - royalsocietypublishing.org
Respiratory tract infections are a major global health concern, accounting for high morbidity
and mortality, especially in young children and elderly individuals. Traditionally, highly …