Osteoarthritis (OA) is a disabling condition that affects billions of people worldwide and
places a considerable burden on patients and on society owing to its prevalence and …

Osteoarthritis (OA) is a chronic joint disease caused by disruption of joint homeostasis by a
variety of systemic and biomechanical factors. The disease is characterized by degradation …

In spite of a major public health burden with increasing prevalence, current osteoarthritis
(OA) management is largely palliative with an unmet need for effective treatment. Both …

Osteoarthritis (OA) can be defined as the result of pathological processes of various
etiologies leading to damage to the articular structures. Although the mechanism of …

The superficial zone of articular cartilage contributes to smooth joint motion through the
production of proteoglycan 4 (PRG4), also known as lubricin. Recent studies indicate novel …

Objective To summarize proceedings of a workshop convened to discuss the current state of
science in the disease of osteoarthritis (OA), identify the knowledge gaps, and examine the …

Osteoarthritis (OA) is a prevalent and severely debilitating disease with an unmet medical
need. In order to alleviate OA symptoms or prevent structural progression of OA, new drugs …

Contemporary treatments for osteoarthritis (OA) pursue only to alleviate the pain caused by
the illness. Discovering disease-modifying osteoarthritis drugs (DMOADs) that can induce …

Osteoarthritis (OA) is the most prevalent arthritis with an estimated global prevalence in
2020 of 22.9%(95% confidence interval [CI], 19.8%-26.1%) in persons over 40 years of age …

Abstract Purpose of Review Osteoarthritis (OA) is the most common forms of arthritis in the
general population, accounting for more pain and functional disability than any other …