The hyaline cartilage is the most abundant type of cartilage in the body. It is responsible for
the bone formation in the embryo (endochondral ossification) and in adults, it can be found …

During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …

Osteoarthritis (OA) is a common joint disease characterized by progressive loss of cartilage
and reduction in lubricating synovial fluid, which lacks effective treatments currently. Here …

Osteoarthritis is a highly prevalent and debilitating joint disorder. There is no effective
medical therapy for the condition because of limited understanding of its pathogenesis. We …

Background: Bone marrow aspirate concentrate (BMAC) is increasingly used as a
regenerative therapy for musculoskeletal pathological conditions despite limited evidence …

The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …

Osteoarthritis (OA), a prevalent chronic condition with a striking impact on quality of life,
represents an enormous societal burden that increases greatly as populations age. Yet no …

Objectives Osteoarthritis (OA) is a degenerative disease characterized by loss of cartilage
and increased subchondral bone within synovial joints. Wnt signaling affects the …

Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

We developed an intra-articular (IA) drug delivery system to treat osteoarthritis (OA) that
consisted of kartogenin conjugated chitosan (CHI-KGN). Kartogenin, which promotes the …