Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that
occurs in response to resistance exercise. A large body of work shows that a mammalian …

It has traditionally been believed that resistance training can only induce muscle growth
when the exercise intensity is greater than 65% of the 1-repetition maximum (RM). However …

Abstract Schoenfeld, BJ, Pope, ZK, Benik, FM, Hester, GM, Sellers, J, Nooner, JL, Schnaiter,
JA, Bond-Williams, KE, Carter, AS, Ross, CL, Just, BL, Henselmans, M, and Krieger, JW …

There has been much debate as to optimal loading strategies for maximising the adaptive
response to resistance exercise. The purpose of this paper therefore was to conduct a meta …

Blood flow restriction (BFR) is an expanding rehabilitation modality that uses a tourniquet to
reduce arterial inflow and occlude venous outflow in the setting of resistance training or …

The α7β1-integrin is a transmembrane adhesion protein that connects laminin in the
extracellular matrix (ECM) with actin in skeletal muscle fibers. The α7β1-integrin is highly …

Metabolic stress is a physiological process that occurs during exercise in response to low
energy that leads to metabolite accumulation [lactate, phosphate inorganic (Pi) and ions of …

Purpose It has been hypothesized that lifting light loads to muscular failure will activate the
full spectrum of MUs and thus bring about muscular adaptations similar to high-load training …

In mammalian systems, skeletal muscle exists in a dynamic state that monitors and regulates
the physiological investment in muscle size to meet the current level of functional demand …