The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

The mesolimbic dopamine system—which originates in the ventral tegmental area and
projects to the striatum—has been shown to be involved in the expression of sex-specific …

Accumulation of neuronal α-synuclein is a prominent feature in Parkinson's disease. More
recently, such abnormal protein aggregation has been reported to spread from cell to cell …

Parkinson's disease (PD) is a chronic, progressive, disabling neurodegenerative disorder
that begins in mid to late life and is characterized by motor impairment, autonomic …

Neurological disorders can be modeled in animals so as to recreate specific pathogenic
events and behavioral outcomes. Parkinson's Disease (PD) is the second most common …

Parkinson's disease (PD) is a neurological movement disorder primarily resulting from
damage to the nigrostriatal dopaminergic pathway. To elucidate the pathogenesis …

Transporters influence the disposition of chemicals within the body by participating in
absorption, distribution, and elimination. Transporters of the solute carrier family (SLC) …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

The SLC22 family contains 13 functionally characterized human plasma membrane proteins
each with 12 predicted α-helical transmembrane domains. The family comprises organic …

Evidence from a variety of studies implicates a role for the adaptive immune system in
Parkinson's disease (PD). Similar to multiple sclerosis (MS) patients who display a high …