From ASCA breakthrough in Crohn's disease and Candida albicans research to thirty years of investigations about their meaning in human health

B Sendid, M Cornu, C Cordier, J Bouckaert… - Autoimmunity …, 2024 - Elsevier
Anti-Saccharomyces cerevisiae antibodies (ASCA) are human antibodies that can be
detected using an enzyme-linked immunosorbent assay involving a mannose polymer …

Application progress of the single domain antibody in medicine

H Tang, Y Gao, J Han - International Journal of Molecular Sciences, 2023 - mdpi.com
The camelid-derived single chain antibody (sdAb), also termed VHH or nanobody, is a
unique, functional heavy (H)-chain antibody (HCAb). In contrast to conventional antibodies …

Modelling the assembly and flexibility of antibody structures

D Guo, ML De Sciscio, JCF Ng, F Fraternali - Current Opinion in Structural …, 2024 - Elsevier
Antibodies are large protein assemblies capable of both specifically recognising antigens
and engaging with other proteins and receptors to coordinate immune action. Traditionally …

Stimbiotics Supplementation Promotes Growth Performance by Improving Plasma Immunoglobulin and IGF-1 Levels and Regulating Gut Microbiota Composition in …

W Chen, C Yin, J Li, W Sun, Y Li, C Wang, Y Pi… - Biology, 2023 - mdpi.com
Simple Summary Recently, stimbiotics (STB) have been suggested as a non-digestible and
fermentable additive that can improve microbial fibre fermentation. This study observed that …

Toward the high-efficient utilization of poultry blood: Insights into functionality, bioactivity and functional components

H Zheng, S Zhao, Y Lu, N Zhang… - Critical Reviews in …, 2024 - Taylor & Francis
A large amount of poultry blood is annually generated, and currently underutilized or largely
disposed of as waste, resulting in environmental pollution and waste of protein resources …

Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein

CD Hodge, DJ Rosenberg, P Grob, M Wilamowski… - MAbs, 2021 - Taylor & Francis
Monoclonal antibodies (mAbs) are the basis of treatments and diagnostics for pathogens
and other biological phenomena. We conducted a structural characterization of mAbs …

Antibodies inhibiting the type III secretion system of Gram-negative pathogenic bacteria

JA Hotinger, AE May - Antibodies, 2020 - mdpi.com
Pathogenic bacteria are a global health threat, with over 2 million infections caused by Gram-
negative bacteria every year in the United States. This problem is exacerbated by the …

Underappreciated layers of antibody-mediated immune synapse architecture and dynamics

BS Goldberg, ME Ackerman - mBio, 2024 - journals.asm.org
The biologic activities of antibody drugs are dictated by structure-function relationships—
emerging from the kind, composition, and degree of interactions with a target antigen and …

Effect of dietary zinc methionine supplementation on growth performance, immune function and intestinal health of Cherry Valley ducks challenged with avian …

Y Chang, J Mei, T Yang, Z Zhang, G Liu… - Frontiers in …, 2022 - frontiersin.org
This study was carried out to evaluate the effects of supplemental zinc methionine (Zn–Met)
on growth performance, immune function, and intestinal health of meat ducks challenged …

IL-1β–dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction

W Yang, EJ Cerier, FL Núñez-Santana… - The Journal of …, 2022 - Am Soc Clin Investig
Preexisting lung-restricted autoantibodies (LRAs) are associated with a higher incidence of
primary graft dysfunction (PGD), although it remains unclear whether LRAs can drive its …