Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

WO2013016486A1 - Nanopore sensors for biomolecular characterization - Google Patents
WO2013016486A1 - Nanopore sensors for biomolecular characterization - Google Patents …

Sensitivity and specificity are two most important factors to take into account for molecule
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …

Dynamics of the nucleosome and exposure of nucleosomal DNA play key roles in many
nuclear processes, but local dynamics of the nucleosome and its modulation by DNA …

Cytosine can undergo modifications, forming 5-methylcytosine (5-mC) and its oxidized
products 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxylcytosine …

Vast numbers of studies and developments in the nanotechnology area have been
conducted and many nanomaterials have been utilized to detect cancers at early stages …

Nucleotide variants, especially those related to epigenetic functions, provide critical
regulatory information beyond simple genomic sequence, and they define cell status in …

Nanopore-based single-molecule detection and analysis have been pursued intensively
over the past decade. One of the most promising applications in this regard is DNA …

A new solid‐state, Al2O3 nanopore sensor with enhanced surface properties for the real‐
time detection and analysis of individual DNA molecules is reported. Nanopore formation …