Thyroid cancer is the most prevalent endocrine malignancy that comprises mostly indolent
differentiated cancers (DTCs) and less frequently aggressive poorly differentiated (PDTC) or …

While long noncoding RNAs (lncRNAs) have been reported to play an important role in
human cancer types, they remain poorly understood in papillary thyroid carcinoma (PTC) …

Results Selected citations revealed the prevalence of MSI in 7.4%, with mutations in the
MSH2 gene (33%) being the most frequent, followed by MSH6 (25%) and MLH1 (16.7%) …

Background: Inactivation of DNA mismatch repair (MMR) and the resulting microsatellite
instability (MSI) are frequently observed in endometrial, stomach, and colorectal cancers, as …

MicroRNAs (miRNAs) are important regulators of multiple cellular processes, and aberrant
miRNA expression has been observed in thyroid cancer. However, the role of miRNAs in …

Abstract O6-methylguanine-DNA methyltransferase (MGMT) has been linked with alkylating
agent resistance and tumor growth suppression. However, its role remains undetermined in …

Long noncoding RNAs (lncRNAs) have emerged as key regulatory molecules at almost
every level of gene expression regulation. The altered expression of lncRNAs is a …

Background Mutations in DNA mismatch repair (MMR) genes associated with thyroid
carcinoma (TC) have rarely been reported, especially in East Asian populations. Methods …

The proto-oncogene PTTG and its binding partner PBF have been widely studied in multiple
cancer types, particularly thyroid and colorectal, but their combined role in tumourigenesis is …

The two main reasons for death of cancer patients, tumor recurrence and metastasis, are
multi-stage cellular processes that involve increased cell plasticity and coincide with …