Background Polypharmacy and use of inappropriate medications have been linked to
increased risk of falls, hospitalizations, cognitive impairment, and death. The primary …

Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

Background: Potentially inappropriate prescribing (PIP) describes medications where risk
generally outweighs benefit for older people. Cross-sectional studies suggest an association …

Objectives Perform a systematic review to evaluate the outcome of deprescription compared
with standard care. The focus was on chronic medical and mental health conditions …

Background There is a rising prevalence of multimorbidity, particularly in older patients, and
a need for evidence-based medicines management interventions for this population. The …

Background Older adults are more vulnerable to polypharmacy and prescriptions of
potentially inappropriate medications. There are several ways to address polypharmacy to …

Importance Polypharmacy and inappropriate drug regimens are major health concerns
among older adults. Various interventions focused on medication optimization strategies …

Background Audit and feedback (A&F) is among the most widely used implementation
strategies, providing healthcare professionals with summaries of their practice performance …

Background Medication‐related adverse events in primary care represent an important
cause of hospital admissions and mortality. Adverse events could result from people …

Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …