Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

In this mini-review, we analyze the influence of cysteines in the structure and activity of
mitochondrial outer membrane mammalian VDAC isoforms. The three VDAC isoforms show …

Abstract α-Linolenic acid (ALA, 18: 3 n-3) and γ-gamma linolenic acid (GLA, 18: 3 n-6) are
polyunsaturated fatty acids (PUFA) that improve the human health. The present study …

Background Endoplasmic reticulum (ER) stress has been implicated in the pathophysiology
of various pulmonary diseases via the activation of the unfolded protein response. However …

We have recently demonstrated that Voltage-dependent anion channel 1 (VDAC1), a protein
located in the mitochondrial outer membrane, is involved in the effects of resveratrol on the …

Circulating cell-free DNA (cfDNA) has been considered an interesting diagnostic/prognostic
plasma biomarker in tumor-bearing subjects. In cancer patients, cfDNA can hypothetically …

Endothelial cell apoptosis and renin-angiotensin-aldosterone system (RAAS) activation are
the major pathological mechanisms for cardiovascular disease and heart failure; however …

Previous studies have shown that early exercise preconditioning (EEP) imparts a protective
effect on acute cardiovascular stress. However, how mitophagy participates in exercise …

Pterostilbene has been found to be an active scaffold with anti-breast cancer (BC) action. In
this study, fourteen pterostilbene-tethered analogues (2A–2N) were prepared and screened …

Objective: This study was to investigate the effects of all-trans retinoic acid (ATRA) in
combination with Genistein on the proliferation, expression of apoptosis related proteins and …