The etiology and pathophysiology genesis of benign prostatic hyperplasia and prostate cancer: a new perspective
TJ Phua - Medicines, 2021 - mdpi.com
Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …
Stem cells as target for prostate cancer therapy: opportunities and challenges
C Escudero-Lourdes, I Alvarado-Morales… - Stem cell reviews and …, 2022 - Springer
Cancer stem cells (CSCs) and cells in a cancer stem cell-like (CSCL) state have proven to
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
[HTML][HTML] microRNA-497 prevents pancreatic cancer stem cell gemcitabine resistance, migration, and invasion by directly targeting nuclear factor kappa B 1
Q Yu, Z Xiu, Y Jian, J Zhou, X Chen, X Chen… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Objectives: Cancer stem cells (CSCs) comprise a small population of cells in cancerous
tumors and play a critical role in tumor resistance to chemotherapy. miRNAs have been …
tumors and play a critical role in tumor resistance to chemotherapy. miRNAs have been …
[PDF][PDF] The m6A methyltransferase METTL3 promotes the stemness and malignant progression of breast cancer by mediating m6A modification on SOX2
J Xie, J Ba, M Zhang, Y Wan, Z Jin, Y Yao - J buon, 2021 - jbuon.com
Purpose: We aimed to uncover the role of METTL3 in stimulating the stemness and
progression of breast cancer (BCa) through mediating N6-methyladenosine (m6A) …
progression of breast cancer (BCa) through mediating N6-methyladenosine (m6A) …
[HTML][HTML] The combination effect of Prominin1 (CD133) suppression and Oxaliplatin treatment in colorectal cancer therapy
Colorectal cancer (CRC) is considered one of the leading types of cancer in the world.
CD133, as a cancer stem cell marker, has a pivotal role in the development of drug …
CD133, as a cancer stem cell marker, has a pivotal role in the development of drug …
Umbelliprenin induces autophagy and apoptosis while inhibits cancer cell stemness in pancreatic cancer cells
H Wang, Y Liu, Y Wang, T Xu, G Xia… - Cancer Medicine, 2023 - Wiley Online Library
Background Umbelliprenin is a sesquiterpene coumarin isolated from Artemisia absinthium
L. and shows antitumor effects in various cancers by inducing apoptosis. However, the …
L. and shows antitumor effects in various cancers by inducing apoptosis. However, the …
Can precancerous stem cells be risk markers for malignant transformation in the oral mucosa?
S Wang, L Ying, SY Yu, J Bai, C Hao - Cellular & Molecular Biology Letters, 2023 - Springer
Accurate assessment of the carcinogenic potential of oral mucosal diseases can significantly
reduce the prevalence of oral cancer. We speculate that precancerous stem cells (pCSCs) …
reduce the prevalence of oral cancer. We speculate that precancerous stem cells (pCSCs) …
Cancer Stem Cells and Prostate Cancer: A Narrative Review
Y Al Salhi, MB Sequi, FM Valenzi, A Fuschi… - International Journal of …, 2023 - mdpi.com
Cancer stem cells (CSCs) are a small and elusive subpopulation of self-renewing cancer
cells with the remarkable ability to initiate, propagate, and spread malignant disease. In the …
cells with the remarkable ability to initiate, propagate, and spread malignant disease. In the …
Tumor architecture and emergence of strong genetic alterations are bottlenecks for clonal evolution in primary prostate cancer
F Kreten, R Büttner, M Peifer, C Harder, AM Hillmer… - Cell Systems, 2024 - cell.com
Prostate cancer (PCA) exhibits high levels of intratumoral heterogeneity. In this study, we
developed a mathematical model to study the growth and genetic evolution of PCA. We …
developed a mathematical model to study the growth and genetic evolution of PCA. We …
lncRNA BORG: TRIM28 complexes drive metastatic progression by inducing α6 integrin/CD49f expression in breast cancer stem cells
KA Parker, AJ Gooding, S Valadkhan… - Molecular Cancer …, 2021 - AACR
Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, with its
aggressive phenotype being attributed to chemotherapy resistance, metastatic …
aggressive phenotype being attributed to chemotherapy resistance, metastatic …