Self-emulsifying drug delivery systems and their marketed products: a review
GV Betageri - Asian Journal of Pharmaceutics (AJP), 2019 - asiapharmaceutics.info
Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …
Development and evaluation of liquid and solid self-emulsifying drug delivery systems for atorvastatin
A Czajkowska-Kośnik, M Szekalska, A Amelian… - Molecules, 2015 - mdpi.com
The objective of this work was to design and characterize liquid and solid self-emulsifying
drug delivery systems (SEDDS) for poorly soluble atorvastatin. To optimize the composition …
drug delivery systems (SEDDS) for poorly soluble atorvastatin. To optimize the composition …
The nasal delivery of nanoencapsulated statins–an approach for brain delivery
A Clementino, M Batger, G Garrastazu… - International journal …, 2016 - Taylor & Francis
Purpose Along with their cholesterol-lowering effect, statins have shown a wide range of
pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such …
pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such …
Coconut oil nanoemulsion loaded with a statin hypolipidemic drug for management of burns: formulation and in vivo evaluation
Burn wound healing is a complex process that involves the repair of injured tissues and the
control of infection to diminish the scar formation, pain, and discomfort associated with such …
control of infection to diminish the scar formation, pain, and discomfort associated with such …
Innovative aqueous nanoemulsion prepared by phase inversion emulsification with exceptional homogeneity
PC Pires, M Fernandes, F Nina, F Gama, MF Gomes… - Pharmaceutics, 2023 - mdpi.com
Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low
administration volumes required in intranasal drug delivery. Nanoemulsions (NE) can solve …
administration volumes required in intranasal drug delivery. Nanoemulsions (NE) can solve …
Impact of solid carriers and spray drying on pre/post-compression properties, dissolution rate and bioavailability of solid self-nanoemulsifying drug delivery system …
In the present study, different solid self-nanoemulsifying drug delivery system (S-SNEDDS)
was formulated by using porous hydrophilic and hydrophobic carriers to improve the …
was formulated by using porous hydrophilic and hydrophobic carriers to improve the …
Improved oral bioavailability of myricitrin by liquid self-microemulsifying drug delivery systems
N Man, Q Wang, H Li, M Adu-Frimpong, C Sun… - Journal of drug delivery …, 2019 - Elsevier
This study aimed to prepare a self-microemulsifying drug delivery system loaded with
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …
Simvastatin in ternary solid dispersion formulations: Improved In vitro dissolution and anti-hyperlipidemia efficiency
MM Mahboobian, S Dadashzadeh, M Rezaei… - Journal of Drug Delivery …, 2022 - Elsevier
Abstract Simvastatin (SIM), an anti-hyperlipidemic agent, has poor solubility and dissolution
rate, resulting in low bioavailability after oral administration. The present study aimed to …
rate, resulting in low bioavailability after oral administration. The present study aimed to …
[HTML][HTML] Evaluation of the efficiency of simvastatin loaded PLGA nanoparticles against acute paraquat-intoxicated rats
Here, we reported a novel nanotherapeutic platform for paraquat (PQ)-induced acute lung
injury in animal models using simvastatin (SV) loaded into Poly (lactic-co-glycolic …
injury in animal models using simvastatin (SV) loaded into Poly (lactic-co-glycolic …
Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth …
Introduction: Essential oil‒based nanoemulsions (NEs) are the subjects of extensive
investigation due to their potential to address a variety of oral health issues. NEs are delivery …
investigation due to their potential to address a variety of oral health issues. NEs are delivery …