Self-emulsifying drug delivery systems and their marketed products: a review

GV Betageri - Asian Journal of Pharmaceutics (AJP), 2019 - asiapharmaceutics.info
Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …

Development and evaluation of liquid and solid self-emulsifying drug delivery systems for atorvastatin

A Czajkowska-Kośnik, M Szekalska, A Amelian… - Molecules, 2015 - mdpi.com
The objective of this work was to design and characterize liquid and solid self-emulsifying
drug delivery systems (SEDDS) for poorly soluble atorvastatin. To optimize the composition …

The nasal delivery of nanoencapsulated statins–an approach for brain delivery

A Clementino, M Batger, G Garrastazu… - International journal …, 2016 - Taylor & Francis
Purpose Along with their cholesterol-lowering effect, statins have shown a wide range of
pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such …

Coconut oil nanoemulsion loaded with a statin hypolipidemic drug for management of burns: formulation and in vivo evaluation

KM Hosny, NA Alhakamy, AM Sindi, RA Khallaf - Pharmaceutics, 2020 - mdpi.com
Burn wound healing is a complex process that involves the repair of injured tissues and the
control of infection to diminish the scar formation, pain, and discomfort associated with such …

Innovative aqueous nanoemulsion prepared by phase inversion emulsification with exceptional homogeneity

PC Pires, M Fernandes, F Nina, F Gama, MF Gomes… - Pharmaceutics, 2023 - mdpi.com
Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low
administration volumes required in intranasal drug delivery. Nanoemulsions (NE) can solve …

Impact of solid carriers and spray drying on pre/post-compression properties, dissolution rate and bioavailability of solid self-nanoemulsifying drug delivery system …

P Sharma, SK Singh, NK Pandey, SY Rajesh, P Bawa… - Powder Technology, 2018 - Elsevier
In the present study, different solid self-nanoemulsifying drug delivery system (S-SNEDDS)
was formulated by using porous hydrophilic and hydrophobic carriers to improve the …

Improved oral bioavailability of myricitrin by liquid self-microemulsifying drug delivery systems

N Man, Q Wang, H Li, M Adu-Frimpong, C Sun… - Journal of drug delivery …, 2019 - Elsevier
This study aimed to prepare a self-microemulsifying drug delivery system loaded with
myricitrin (M-SMEDDS) to improve the low oral bioavailability of myricitrin. Prepared M …

Simvastatin in ternary solid dispersion formulations: Improved In vitro dissolution and anti-hyperlipidemia efficiency

MM Mahboobian, S Dadashzadeh, M Rezaei… - Journal of Drug Delivery …, 2022 - Elsevier
Abstract Simvastatin (SIM), an anti-hyperlipidemic agent, has poor solubility and dissolution
rate, resulting in low bioavailability after oral administration. The present study aimed to …

[HTML][HTML] Evaluation of the efficiency of simvastatin loaded PLGA nanoparticles against acute paraquat-intoxicated rats

M Moshiri, F Mehmannavaz, M Hashemi… - European Journal of …, 2022 - Elsevier
Here, we reported a novel nanotherapeutic platform for paraquat (PQ)-induced acute lung
injury in animal models using simvastatin (SV) loaded into Poly (lactic-co-glycolic …

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth …

M Alissa, A Hjazi, GS Abusalim, GS Aloraini… - Frontiers in …, 2024 - frontiersin.org
Introduction: Essential oil‒based nanoemulsions (NEs) are the subjects of extensive
investigation due to their potential to address a variety of oral health issues. NEs are delivery …