Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …

Experimental models of acute kidney injury for translational research

NA Hukriede, DE Soranno, V Sander… - Nature Reviews …, 2022 - nature.com
Preclinical models of human disease provide powerful tools for therapeutic discovery but
have limitations. This problem is especially apparent in the field of acute kidney injury (AKI) …

Caution on kidney dysfunctions of COVID-19 patients

Z Li, M Wu, J Yao, J Guo, X Liao, S Song, J Li, G Duan… - MedRxiv, 2020 - medrxiv.org
Background To date, large amounts of epidemiological and case study data have been
available for the Coronavirus Disease 2019 (COVID-19), which suggested that the mortality …

Identification of kidney injury–released circulating osteopontin as causal agent of respiratory failure

FZ Khamissi, L Ning, E Kefaloyianni, H Dun… - Science …, 2022 - science.org
Tissue injury can drive secondary organ injury; however, mechanisms and mediators are not
well understood. To identify interorgan cross-talk mediators, we used acute kidney injury …

Epidemiology and outcomes of acute kidney injury in COVID-19 patients with acute respiratory distress syndrome: a multicenter retrospective study

F Wang, L Ran, C Qian, J Hua, Z Luo, M Ding… - Blood purification, 2021 - karger.com
Background: Acute kidney injury (AKI) is associated with increased mortality in patients with
acute respiratory distress syndrome (ARDS). However, the epidemiological features and …

Organ crosstalk in acute kidney injury: evidence and mechanisms

X Li, F Yuan, L Zhou - Journal of Clinical Medicine, 2022 - mdpi.com
Acute kidney injury (AKI) is becoming a public health problem worldwide. AKI is usually
considered a complication of lung, heart, liver, gut, and brain disease, but recent findings …

Incidence and risk factors of kidney impairment on patients with COVID-19: A meta-analysis of 10180 patients

Q Yang, X Yang - PLoS One, 2020 - journals.plos.org
Background The novel coronavirus is pandemic around the world. Several researchers have
given the evidence of impacts of COVID-19 on the respiratory, cardiovascular and …

Interorgan communication networks in the kidney–lung axis

Y Komaru, YZ Bai, D Kreisel, A Herrlich - Nature Reviews Nephrology, 2024 - nature.com
The homeostasis and health of an organism depend on the coordinated interaction of
specialized organs, which is regulated by interorgan communication networks of circulating …

Intensive Care Unit–Acquired Weakness in Patients With Acute Kidney Injury: A Contemporary Review

JP Teixeira, KP Mayer, BR Griffin, N George… - American journal of …, 2023 - Elsevier
Acute kidney injury (AKI) and intensive care unit–acquired weakness (ICU-AW) are 2
frequent complications of critical illness that, until recently, have been considered unrelated …

Development of a Risk Score for AKI onset in COVID-19 Patients: COV-AKI Score

H Palomba, D Cubos, F Bozza, FG Zampieri… - BMC nephrology, 2023 - Springer
Abstract Purpose Acute Kidney Injury (AKI) in COVID-19 patients is associated with
increased morbidity and mortality. In the present study, we aimed to develop a prognostic …