Azole‐resistant Aspergillus fumigatus as an emerging worldwide pathogen
SM Rivelli Zea, T Toyotome - Microbiology and Immunology, 2022 - Wiley Online Library
Aspergillus fumigatus, a ubiquitous pathogen, causes aspergillosis in humans, especially in
immunodeficient patients. Azoles are frontline antifungal drugs for treating aspergillosis. The …
immunodeficient patients. Azoles are frontline antifungal drugs for treating aspergillosis. The …
Current and emerging technologies to develop Point-of-Care Diagnostics in medical mycology
Introduction Advances in diagnostic technologies, particularly Point-of-Care Diagnostics
(POCDs), have revolutionized clinical practice by providing rapid, user-friendly, and …
(POCDs), have revolutionized clinical practice by providing rapid, user-friendly, and …
Antifungal drug resistance: an update
DW Denning - European Journal of Hospital Pharmacy, 2022 - ejhp.bmj.com
The number of antifungal classes is small, and resistance is becoming a much more
frequent problem. Much greater emphasis needs to be placed on susceptibility testing and …
frequent problem. Much greater emphasis needs to be placed on susceptibility testing and …
Overview of antimicrobial resistance: an emerging silent pandemic
Before the outbreak of Coronavirus disease-19, one of the top 10 most risks identified by the
World Health Organization (WHO) is antimicrobial resistance (AMR) that is also known as …
World Health Organization (WHO) is antimicrobial resistance (AMR) that is also known as …
The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus
A Kühbacher, P Merschak, H Haas… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Azole antifungals remain the “gold standard” therapy for invasive aspergillosis. The world-
wide emergence of isolates resistant to this drug class, however, developed into a steadily …
wide emergence of isolates resistant to this drug class, however, developed into a steadily …
Longitudinal multimodal imaging-compatible mouse model of triazole-sensitive and-resistant invasive pulmonary aspergillosis
A Resendiz-Sharpe, RP da Silva… - Disease models & …, 2022 - journals.biologists.com
Invasive pulmonary aspergillosis (IPA) caused by the mold Aspergillus fumigatus is one of
the most important life-threatening infections in immunocompromised patients. The alarming …
the most important life-threatening infections in immunocompromised patients. The alarming …
Epidemiology, drug susceptibility, and clinical risk factors in patients with invasive aspergillosis
Y Wang, L Zhang, L Zhou, M Zhang, Y Xu - Frontiers in Public Health, 2022 - frontiersin.org
Background This study aimed to investigate the Aspergillus species distribution, antifungal
sensitivities, clinical characteristics, and risk factors of patients with invasive aspergillosis …
sensitivities, clinical characteristics, and risk factors of patients with invasive aspergillosis …
Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14α-Sterol Demethylase, Leads to Triazole Resistance
M Handelman, Z Meir, J Scott… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Aspergillus fumigatus is the most common cause of invasive fungal mold infections in
immunocompromised individuals. Current antifungal treatment relies heavily on the triazole …
immunocompromised individuals. Current antifungal treatment relies heavily on the triazole …
hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate
ACO Souza, W Ge, NP Wiederhold… - Microbiology …, 2023 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous environmental mold that can cause severe disease in
immunocompromised patients and chronic disease in individuals with underlying lung …
immunocompromised patients and chronic disease in individuals with underlying lung …
Potential Mechanisms of Hexaconazole Resistance in Fusarium graminearum
F Zhou, X Zhou, Y Jiao, A Han, H Su, L Wang… - Plant …, 2024 - Am Phytopath Society
Fusarium head blight (FHB) caused by Fusarium graminearum is a serious fungal disease
that can dramatically impact wheat production. At present, disease control is mainly …
that can dramatically impact wheat production. At present, disease control is mainly …