Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites

RM de Jong, SK Tebeje… - Immunological …, 2020 - Wiley Online Library
The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

The burden of submicroscopic and asymptomatic malaria in India revealed from epidemiology studies at three varied transmission sites in India

AM van Eijk, PL Sutton, L Ramanathapuram… - Scientific reports, 2019 - nature.com
Malaria in India, while decreasing, remains a serious public health problem, and the
contribution of submicroscopic and asymptomatic infections to its persistence is poorly …

Protocols for Plasmodium gametocyte production in vitro: an integrative review and analysis

R Omorou, I Bin Sa'id, M Delves, C Severini… - Parasites & …, 2022 - Springer
Abstract Background The production of Plasmodium gametocytes in vitro is a real challenge.
Many protocols have been described, but few have resulted in the production of viable and …

Plasmodium falciparum Development from Gametocyte to Oocyst: Insight from Functional Studies

DT Ouologuem, A Dara, A Kone, A Ouattara… - Microorganisms, 2023 - mdpi.com
Malaria elimination may never succeed without the implementation of transmission-blocking
strategies. The transmission of Plasmodium spp. parasites from the human host to the …

Gametocyte carriage of Plasmodium falciparum (pfs25) and Plasmodium vivax (pvs25) during mass screening and treatment in West Timor, Indonesia: a …

A Kosasih, C Koepfli, MS Dahlan, WA Hawley, JK Baird… - Malaria Journal, 2021 - Springer
Background A goal of malaria epidemiological interventions is the detection and treatment of
parasite reservoirs in endemic areas—an activity that is expected to reduce local …

Global metabolomic profiling of host red blood cells infected with Babesia divergens reveals novel antiparasitic target pathways

D Beri, M Singh, M Rodriguez, N Goyal… - Microbiology …, 2023 - Am Soc Microbiol
Babesia divergens is an apicomplexan parasite that infects human red blood cells (RBCs),
initiating cycles of invasion, replication, and egress, resulting in extensive metabolic …

In vitro reduction of Plasmodium falciparum gametocytes: Artemisia spp. tea infusions vs. artemisinin

D Snider, PJ Weathers - Journal of ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Artemisia annua has a long history of use in Southeast
Asia where it was used to treat “fever”, and A. afra has a similar history in southern Africa …

Sex in protists: A new perspective on the reproduction mechanisms of trypanosomatids

VS Silva, CR Machado - Genetics and molecular biology, 2022 - SciELO Brasil
The Protist kingdom individuals are the most ancestral representatives of eukaryotes. They
have inhabited Earth since ancient times and are currently found in the most diverse …

High-throughput analysis of the transcriptional patterns of sexual genes in malaria

A Cruz Camacho, E Kiper, S Oren, N Zaharoni, N Nir… - Parasites & vectors, 2023 - Springer
Abstract Background Plasmodium falciparum (Pf) is the leading protozoan causing malaria,
the most devastating parasitic disease. To ensure transmission, a small subset of Pf …