Wound healing: a cellular perspective

M Rodrigues, N Kosaric, CA Bonham… - Physiological …, 2019 - journals.physiology.org
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

The impact of diabetes on periodontal diseases

DT Graves, Z Ding, Y Yang - Periodontology 2000, 2020 - Wiley Online Library
The susceptibility and severity of periodontal diseases is made more severe by diabetes,
with the impact on the disease process inversely proportional to the level of glycemic control …

Green tea derivative driven smart hydrogels with desired functions for chronic diabetic wound treatment

X Zhao, D Pei, Y Yang, K Xu, J Yu… - Advanced functional …, 2021 - Wiley Online Library
Current treatments for chronic diabetic wounds remain unsatisfactory due to the lack of ideal
wound dressings that can integrate matching mechanical strength, fast self‐healability, facile …

ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds

H Zhao, J Huang, Y Li, X Lv, H Zhou, H Wang, Y Xu… - Biomaterials, 2020 - Elsevier
Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal
diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or …

[HTML][HTML] The microbiome in patients with atopic dermatitis

AS Paller, HH Kong, P Seed, S Naik… - Journal of Allergy and …, 2019 - Elsevier
As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …

The oral microbiota is modified by systemic diseases

DT Graves, JD Corrêa, TA Silva - Journal of dental research, 2019 - journals.sagepub.com
Periodontal diseases are initiated by bacteria that accumulate in a biofilm on the tooth
surface and affect the adjacent periodontal tissue. Systemic diseases such as diabetes …

Wound repair and regeneration: mechanisms, signaling, and translation

SA Eming, P Martin, M Tomic-Canic - Science translational medicine, 2014 - science.org
The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

SL Wong, M Demers, K Martinod, M Gallant, Y Wang… - Nature medicine, 2015 - nature.com
Wound healing is impaired in diabetes, resulting in significant morbidity and mortality.
Neutrophils are the main leukocytes involved in the early phase of healing. As part of their …

Epithelialization in wound healing: a comprehensive review

I Pastar, O Stojadinovic, NC Yin, H Ramirez… - Advances in wound …, 2014 - liebertpub.com
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

S Naik, N Bouladoux, JL Linehan, SJ Han, OJ Harrison… - Nature, 2015 - nature.com
The skin represents the primary interface between the host and the environment. This organ
is also home to trillions of microorganisms that play an important role in tissue homeostasis …