Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography
H Komatsu, G Onoguchi, SM Silverstein, S Jerotic… - Molecular …, 2024 - nature.com
Introduction Abnormal findings on optical coherence tomography (OCT) and
electroretinography (ERG) have been reported in participants with schizophrenia spectrum …
electroretinography (ERG) have been reported in participants with schizophrenia spectrum …
Association between retinal features from multimodal imaging and schizophrenia
Importance The potential association of schizophrenia with distinct retinal changes is of
clinical interest but has been challenging to investigate because of a lack of sufficiently large …
clinical interest but has been challenging to investigate because of a lack of sufficiently large …
[HTML][HTML] Optical coherence tomography in schizophrenia spectrum disorders: A systematic review and meta-analysis
W Shew, DJ Zhang, DB Menkes… - … Psychiatry Global Open …, 2024 - Elsevier
Background Inner retinal atrophy has been demonstrated in schizophrenia spectrum
disorder (SSD) using optical coherence tomography (OCT). This systematic review and meta …
disorder (SSD) using optical coherence tomography (OCT). This systematic review and meta …
Inflammatory subtypes in antipsychotic-naïve first-episode schizophrenia are associated with altered brain morphology and topological organization
Background Peripheral inflammation is implicated in schizophrenia, however, not all
individuals demonstrate inflammatory alterations. Recent studies identified inflammatory …
individuals demonstrate inflammatory alterations. Recent studies identified inflammatory …
Neuroretinal alterations in schizophrenia and bipolar disorder: an updated meta-analysis
N Sheehan, D Bannai, SM Silverstein… - Schizophrenia …, 2024 - academic.oup.com
Schizophrenia (SZ) and bipolar disorder (BD) are characterized by major symptomatic,
cognitive, and neuroanatomical changes. Recent studies have used optical coherence …
cognitive, and neuroanatomical changes. Recent studies have used optical coherence …
Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders
E Boudriot, B Schworm, L Slapakova, K Hanken… - European Archives of …, 2023 - Springer
Abstract Background Schizophrenia spectrum disorders (SSDs) are presumed to be
associated with retinal thinning. However, evidence is lacking as to whether these retinal …
associated with retinal thinning. However, evidence is lacking as to whether these retinal …
Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular …
S Puvogel, A Alsema, L Kracht, MJ Webster… - Molecular …, 2022 - nature.com
The midbrain is an extensively studied brain region in schizophrenia, in view of its reported
dopamine pathophysiology and neuroimmune changes associated with this disease …
dopamine pathophysiology and neuroimmune changes associated with this disease …
[HTML][HTML] Association between polygenic risk for schizophrenia and retinal morphology: A cross-sectional analysis of the United Kingdom Biobank
We examined the relationship between genetic risk for schizophrenia (SZ), using polygenic
risk scores (PRSs), and retinal morphological alterations. Retinal structural and vascular …
risk scores (PRSs), and retinal morphological alterations. Retinal structural and vascular …
Deep learning model using retinal vascular images for classifying schizophrenia
Contemporary psychiatric diagnosis still relies on the subjective symptom report of the
patient during a clinical interview by a psychiatrist. Given the significant variability in …
patient during a clinical interview by a psychiatrist. Given the significant variability in …
OCT and OCT angiography offer new insights and opportunities in schizophrenia research and treatment
KM Green, JJ Choi, RS Ramchandran… - Frontiers in digital …, 2022 - frontiersin.org
The human retina and retinal imaging technologies continue to increasingly gain the
attention of schizophrenia researchers. With the same embryologic origin as the brain, the …
attention of schizophrenia researchers. With the same embryologic origin as the brain, the …