Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. It is a well-recognized multifactorial health problem contributes significantly to high …

Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …

Diabetes is one of the major diseases worldwide and is the third leading cause of death in
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …

New types of antidiabetic agents are continually needed with diabetes becoming the
epidemic in the world. Indole alkaloids play an important role in natural products owing to …

Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …

Abstract New quinoxaline derivative, N-(4-methyl-2-nitrophenyl)-2-(3-methyl-2-
oxoquinoxalin-1 (2H)-yl) acetamide (NPOQA) has been synthesized and characterized by …

The development of new small molecules from known structural motifs through molecular
hybridization is one of the trends in drug discovery. In this connection, we have combined …

One of the most prevailing metabolic disorder diabetes mellitus has become the global
health issue that has to be addressed and cured. Different marketed drugs have been made …

Dipeptidyl peptidase-IV (DPP-IV) inhibitors, often known as gliptins, have been used to treat
type 2 diabetes mellitus (T2DM). They may be combined with other medications as an …