An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment

YY Cheok, CYQ Lee, HC Cheong, J Vadivelu, CY Looi… - Microorganisms, 2021 - mdpi.com
Helicobacter pylori is well established as a causative agent for gastritis, peptic ulcer, and
gastric cancer. Armed with various inimitable virulence factors, this Gram-negative bacterium …

The roles of immune cells in gastric cancer: anti-cancer or pro-cancer?

A Sukri, A Hanafiah, NR Kosai - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer is still one of the leading causes of death caused by cancer
in developing countries. The emerging role of immunotherapy in cancer treatment has led to …

Helicobacter pylori Eradication Causes Perturbation of the Human Gut Microbiome in Young Adults

TWC Yap, HM Gan, YP Lee, AHR Leow, AN Azmi… - PloS one, 2016 - journals.plos.org
Background Accumulating evidence shows that Helicobacter pylori protects against some
metabolic and immunological diseases in which the development of these diseases …

Lactobacillus fermentum and its potential immunomodulatory properties

Y Zhao, K Hong, J Zhao, H Zhang, Q Zhai… - Journal of Functional …, 2019 - Elsevier
Lactobacillus fermentum has been used in industrial processes and food fermentation for a
long time. Because it is of human origin, non-pathogenic, has high resistance to passing …

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

BM Cumming, MA Rahman, DA Lamprecht… - PLoS …, 2017 - journals.plos.org
Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors
essential for establishing long-term persistent infection are unknown. The WhiB3 redox …

New insight on the role of Helicobacter pylori cagA in the expression of cell surface antigens with important biological functions in gastric carcinogenesis

A Sukri, A Hanafiah, NR Kosai… - …, 2022 - Wiley Online Library
Background Expression of cluster of differentiation (CD) antigens changes according to
disease status and inflammation. Profiles of CD antigens expression in gastric cancer …

Regulation of epigenetic modifiers, including KDM6B, by interferon-γ and interleukin-4 in human macrophages

G Yıldırım-Buharalıoğlu, M Bond… - Frontiers in …, 2017 - frontiersin.org
Background Interferon-γ (IFN-γ) or interleukin-4 (IL-4) drives widely different transcriptional
programs in macrophages. However, how IFN-γ and IL-4 alter expression of histone …

Podoplanin Drives Motility of Active Macrophage via Regulating Filamin C During Helicobacter pylori Infection

YY Cheok, GMY Tan, KC Fernandez, YT Chan… - Frontiers in …, 2021 - frontiersin.org
Podoplanin (Pdpn) is a mucin-type transmembrane protein that has been implicated in
multiple physiological settings including lymphangiogenesis, platelet aggregation, and …

Macrophage biology in the pathogenesis of Helicobacter pylori infection

X Fei, N Li, X Xu, Y Zhu - Critical Reviews in Microbiology, 2024 - Taylor & Francis
Infection with H. pylori induces chronic gastric inflammation, progressing to peptic ulcer and
stomach adenocarcinoma. Macrophages function as innate immune cells and play a vital …

Helicobacter pylori virulence factors: subversion of host immune system and development of various clinical outcomes

R Mohammadzadeh, S Menbari… - Expert Reviews in …, 2023 - cambridge.org
Helicobacter pylori (H. pylori) is a worldwide spread bacterium, co-evolving with humans for
at least 100 000 years. Despite the uncertainty about the mode of H. pylori transmission, the …