Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Use of brain biomechanical models for monitoring impact exposure in contact sports

S Ji, M Ghajari, H Mao, RH Kraft… - Annals of Biomedical …, 2022 - Springer
Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …

Standard‐space atlas of the viscoelastic properties of the human brain

LV Hiscox, MDJ McGarry, H Schwarb… - Human brain …, 2020 - Wiley Online Library
Standard anatomical atlases are common in neuroimaging because they facilitate data
analyses and comparisons across subjects and studies. The purpose of this study was to …

Principal-stretch-based constitutive neural networks autonomously discover a subclass of Ogden models for human brain tissue

SRS Pierre, K Linka, E Kuhl - Brain Multiphysics, 2023 - Elsevier
The soft tissue of the brain deforms in response to external stimuli, which can lead to
traumatic brain injury. Constitutive models relate the stress in the brain to its deformation and …

Instantaneous whole-brain strain estimation in dynamic head impact

K Ghazi, S Wu, W Zhao, S Ji - Journal of Neurotrauma, 2021 - liebertpub.com
Head injury models are notoriously time consuming and resource demanding in simulations,
which prevents routine application. Here, we extend a convolutional neural network (CNN) …

An analytical review of the numerical methods used for finite element modeling of traumatic brain injury

JS Giudice, W Zeng, T Wu, A Alshareef… - Annals of biomedical …, 2019 - Springer
Dozens of finite element models of the human brain have been developed for providing
insight into the mechanical response of the brain during impact. Many models used in …

Finite element methods in human head impact simulations: a review

A Madhukar, M Ostoja-Starzewski - Annals of biomedical engineering, 2019 - Springer
Head impacts leading to traumatic brain injury (TBI) present a major health risk today,
projected to become the third leading cause of death by 2020. While finite element (FE) …

Explicit modeling of white matter axonal fiber tracts in a finite element brain model

T Wu, A Alshareef, JS Giudice, MB Panzer - Annals of biomedical …, 2019 - Springer
Many human brain finite element (FE) models lack mesoscopic (~ 1 mm) white matter
structures, which may limit their capability in predicting TBI and assessing tissue-based …

Convolutional neural network for efficient estimation of regional brain strains

S Wu, W Zhao, K Ghazi, S Ji - Scientific reports, 2019 - nature.com
Head injury models are important tools to study concussion biomechanics but are
impractical for real-world use because they are too slow. Here, we develop a convolutional …

A novel bio-inspired helmet with auxetic lattice liners for mitigating traumatic brain injury

Z Chen, J Li, B Wu, X Chen, X Ren… - Smart materials and …, 2023 - iopscience.iop.org
The human head is most vulnerable to injury during activities such as road traffic and sports.
To mitigate the risk of traumatic brain injury (TBI), helmets serve as an important protective …