Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

Polymeric nanoparticle based diagnosis and nanomedicine for treatment and development of vaccines for cerebral malaria: a review on recent advancement

S Patra, M Singh, K Wasnik, D Pareek… - ACS Applied Bio …, 2021 - ACS Publications
Cerebral malaria occurs due to Plasmodium falciparum infection, which causes 228 million
infections and 450,000 deaths worldwide every year. African people are mostly affected with …

[HTML][HTML] Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis

A Rehman, S Ahmad, F Shahid, A Albutti… - Vaccines, 2021 - mdpi.com
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …

[HTML][HTML] Designing a next generation multi-epitope based peptide vaccine candidate against SARS-CoV-2 using computational approaches

R Saha, P Ghosh, VLSP Burra - 3 Biotech, 2021 - Springer
COVID-19 caused by SARS-CoV-2 was declared a global pandemic by WHO (World Health
Organization) in March, 2020. Within 6 months, nearly 750,000 deaths are claimed by …

Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing

P Jaishwal, K Jha, SP Singh - International Journal of Biological …, 2024 - Elsevier
Even though the use of SARS-CoV-2 vaccines during the COVID-19 pandemic showed
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …

A multi‐epitope chimeric protein elicited a strong antibody response and partial protection against Edwardsiella ictaluri in Nile tilapia

VI Machimbirike, N Pornputtapong… - Journal of fish …, 2022 - Wiley Online Library
Edwardsiella ictaluri infects several fish species and protection of the all the susceptible fish
hosts from the pathogen using a monovalent vaccine is impossible because the species is …

Computational analysis of spike protein of SARS-CoV-2 (Omicron variant) for development of peptide-based therapeutics and diagnostics

M Pritam, S Dutta, KM Medicherla… - Journal of …, 2023 - Taylor & Francis
In the last few years, the worldwide population has suffered from the SARS-CoV-2
pandemic. The WHO dashboard indicated that around 504,079,039 people were infected …

Trypanosoma cruzi Tc24 Antigen Expressed and Orally Delivered by Schizochytrium sp. Microalga is Immunogenic in Mice

A Ramos-Vega, E Monreal-Escalante… - Molecular …, 2024 - Springer
Chagas disease—caused by the parasite Trypanosoma cruzi—is a neglected tropical
disease for which available drugs are not fully effective in the chronic stage and a vaccine is …

[HTML][HTML] Alum pickering emulsion as effective adjuvant to improve malaria vaccine efficacy

Q Chen, N Wu, Y Gao, X Wang, J Wu, G Ma - Vaccines, 2021 - mdpi.com
Malaria is a life-threatening global epidemic disease and has caused more than 400,000
deaths in 2019. To control and prevent malaria, the development of a vaccine is a potential …

Structural immunoinformatics approach for rational design of a multi-epitope vaccine against triple negative breast cancer

T Dhanushkumar, B Kamaraj, K Vasudevan… - International Journal of …, 2023 - Elsevier
TNBC is a highly malignant breast cancer known for its aggressive behavior affecting young
female adults. The standard treatment for TNBC includes surgery, chemotherapy, and …