Neuronal cellular nanosponges for effective detoxification of neurotoxins

D Wang, X Ai, Y Duan, N Xian, RH Fang, W Gao… - ACS …, 2022 - ACS Publications
Neurotoxins attack and destruct the nervous system, which can cause serious health
problems and security threats. Existing detoxification approaches, such as antibodies and …

Viscoelastic chondroitin sulfate and hyaluronic acid double-network hydrogels with reversible cross-links

M Mihajlovic, M Rikkers, M Mihajlovic, M Viola… - …, 2022 - ACS Publications
Viscoelastic hydrogels are gaining interest as they possess necessary requirements for
bioprinting and injectability. By means of reversible, dynamic covalent bonds, it is possible to …

[HTML][HTML] Control of hydrostatic pressure and osmotic stress in 3D cell culture for mechanobiological studies

AP Kourouklis, A Wahlsten, A Stracuzzi, A Martyts… - Biomaterials …, 2023 - Elsevier
Hydrostatic pressure (HP) and osmotic stress (OS) play an important role in various
biological processes, such as cell proliferation and differentiation. In contrast to canonical …

[HTML][HTML] Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold

KA Pitrolino, RM Felfel, LM Pellizzeri, J McLaren… - Carbohydrate …, 2022 - Elsevier
An innovative approach was developed to engineer a multi-layered chitosan scaffold for
osteochondral defect repair. A combination of freeze drying and porogen-leaching out …

Double-edged role of mechanical stimuli and underlying mechanisms in cartilage tissue engineering

Y Jia, H Le, X Wang, J Zhang, Y Liu, J Ding… - … in Bioengineering and …, 2023 - frontiersin.org
Mechanical stimuli regulate the chondrogenic differentiation of mesenchymal stem cells and
the homeostasis of chondrocytes, thus affecting implant success in cartilage tissue …

The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination

GS Offeddu, C Hajal, CR Foley, Z Wan… - Communications …, 2021 - nature.com
The glycocalyx on tumor cells has been recently identified as an important driver for cancer
progression, possibly providing critical opportunities for treatment. Metastasis, in particular …

Protein‐Loaded Cellular Nanosponges for Dual‐Biomimicry Neurotoxin Countermeasure

S Wang, D Wang, WT Shen, M Kai, Y Yu, Y Peng… - Small, 2024 - Wiley Online Library
Neurotoxins present a substantial threat to human health and security as they disrupt and
damage the nervous system. Their potent and structurally diverse nature poses challenges …

Development and characterisation of microporous biomimetic scaffolds loaded with magnetic nanoparticles as bone repairing material

FD Cojocaru, V Balan, CE Tanase, IM Popa… - Ceramics …, 2021 - Elsevier
Fine-tuning of the scaffolds structural features for bone tissue engineering can be an efficient
approach to regulate the specific response of the osteoblasts. Here, we loaded magnetic …

Scale and structure dependent solute diffusivity within microporous tissue engineering scaffolds

GS Offeddu, L Mohee, RE Cameron - Journal of Materials Science …, 2020 - Springer
Diffusion of nutrients to cells cultured within three-dimensional scaffolds is fundamental for
cell survival during development of the tissue construct, when no vasculature is present to …

Hydrogels with tunable physical cues and their emerging roles in studies of cellular mechanotransduction

BN Narasimhan, MS Horrocks… - Advanced NanoBiomed …, 2021 - Wiley Online Library
The extracellular matrix provides complex biophysical cues to cells which respond to these
signals with signaling cascades that determine various cellular processes including fate …