Neuronal cellular nanosponges for effective detoxification of neurotoxins
Neurotoxins attack and destruct the nervous system, which can cause serious health
problems and security threats. Existing detoxification approaches, such as antibodies and …
problems and security threats. Existing detoxification approaches, such as antibodies and …
Viscoelastic chondroitin sulfate and hyaluronic acid double-network hydrogels with reversible cross-links
M Mihajlovic, M Rikkers, M Mihajlovic, M Viola… - …, 2022 - ACS Publications
Viscoelastic hydrogels are gaining interest as they possess necessary requirements for
bioprinting and injectability. By means of reversible, dynamic covalent bonds, it is possible to …
bioprinting and injectability. By means of reversible, dynamic covalent bonds, it is possible to …
[HTML][HTML] Control of hydrostatic pressure and osmotic stress in 3D cell culture for mechanobiological studies
AP Kourouklis, A Wahlsten, A Stracuzzi, A Martyts… - Biomaterials …, 2023 - Elsevier
Hydrostatic pressure (HP) and osmotic stress (OS) play an important role in various
biological processes, such as cell proliferation and differentiation. In contrast to canonical …
biological processes, such as cell proliferation and differentiation. In contrast to canonical …
[HTML][HTML] Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold
KA Pitrolino, RM Felfel, LM Pellizzeri, J McLaren… - Carbohydrate …, 2022 - Elsevier
An innovative approach was developed to engineer a multi-layered chitosan scaffold for
osteochondral defect repair. A combination of freeze drying and porogen-leaching out …
osteochondral defect repair. A combination of freeze drying and porogen-leaching out …
Double-edged role of mechanical stimuli and underlying mechanisms in cartilage tissue engineering
Y Jia, H Le, X Wang, J Zhang, Y Liu, J Ding… - … in Bioengineering and …, 2023 - frontiersin.org
Mechanical stimuli regulate the chondrogenic differentiation of mesenchymal stem cells and
the homeostasis of chondrocytes, thus affecting implant success in cartilage tissue …
the homeostasis of chondrocytes, thus affecting implant success in cartilage tissue …
The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination
The glycocalyx on tumor cells has been recently identified as an important driver for cancer
progression, possibly providing critical opportunities for treatment. Metastasis, in particular …
progression, possibly providing critical opportunities for treatment. Metastasis, in particular …
Protein‐Loaded Cellular Nanosponges for Dual‐Biomimicry Neurotoxin Countermeasure
Neurotoxins present a substantial threat to human health and security as they disrupt and
damage the nervous system. Their potent and structurally diverse nature poses challenges …
damage the nervous system. Their potent and structurally diverse nature poses challenges …
Development and characterisation of microporous biomimetic scaffolds loaded with magnetic nanoparticles as bone repairing material
Fine-tuning of the scaffolds structural features for bone tissue engineering can be an efficient
approach to regulate the specific response of the osteoblasts. Here, we loaded magnetic …
approach to regulate the specific response of the osteoblasts. Here, we loaded magnetic …
Scale and structure dependent solute diffusivity within microporous tissue engineering scaffolds
GS Offeddu, L Mohee, RE Cameron - Journal of Materials Science …, 2020 - Springer
Diffusion of nutrients to cells cultured within three-dimensional scaffolds is fundamental for
cell survival during development of the tissue construct, when no vasculature is present to …
cell survival during development of the tissue construct, when no vasculature is present to …
Hydrogels with tunable physical cues and their emerging roles in studies of cellular mechanotransduction
BN Narasimhan, MS Horrocks… - Advanced NanoBiomed …, 2021 - Wiley Online Library
The extracellular matrix provides complex biophysical cues to cells which respond to these
signals with signaling cascades that determine various cellular processes including fate …
signals with signaling cascades that determine various cellular processes including fate …