Glucose transporters at the blood-brain barrier: function, regulation and gateways for drug delivery

SG Patching - Molecular neurobiology, 2017 - Springer
Glucose transporters (GLUTs) at the blood-brain barrier maintain the continuous high
glucose and energy demands of the brain. They also act as therapeutic targets and provide …

The main molecular mechanisms underlying methamphetamine-induced neurotoxicity and implications for pharmacological treatment

X Yang, Y Wang, Q Li, Y Zhong, L Chen… - Frontiers in molecular …, 2018 - frontiersin.org
Methamphetamine (METH) is a popular new-type psychostimulant drug with complicated
neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the …

Pharmacological treatments for methamphetamine addiction: current status and future directions

J Ballester, G Valentine, M Sofuoglu - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Methamphetamine (MA) abuse remains a global health challenge despite
intense research interest in the development of pharmacological treatments. This review …

Neuroimmune basis of methamphetamine toxicity

JM Loftis, A Janowsky - International review of neurobiology, 2014 - Elsevier
Although it is not known which antigen-specific immune responses (or if antigen-specific
immune responses) are relevant or required for methamphetamine's neurotoxic effects, it is …

Toll-like receptor 4 mediates methamphetamine-induced neuroinflammation through caspase-11 signaling pathway in astrocytes

SH Du, DF Qiao, CX Chen, S Chen, C Liu… - Frontiers in molecular …, 2017 - frontiersin.org
Methamphetamine (METH) is an amphetamine-typed stimulant drug that is increasingly
being abused worldwide. Previous studies have shown that METH toxicity is systemic …

CB1R-dependent regulation of astrocyte physiology and astrocyte-neuron interactions

A Covelo, A Eraso-Pichot, I Fernandez-Moncada… - …, 2021 - Elsevier
The endocannabinoid system (ECS) is involved in a variety of brain functions, mainly
through the activation of the type-1 cannabinoid receptors (CB1R). CB1R are highly …

Carnitine derivatives: clinical usefulness

M Malaguarnera - Current opinion in gastroenterology, 2012 - journals.lww.com
Carnitine derivatives: clinical usefulness : Current Opinion in Gastroenterology Carnitine
derivatives: clinical usefulness : Current Opinion in Gastroenterology Log in or Register …

Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis

LP Shriver, M Manchester - Scientific reports, 2011 - nature.com
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
and a leading cause of neurological disability. The complex immunopathology and variable …

Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats

A Karalija, LN Novikova, PJ Kingham, M Wiberg… - PLoS …, 2012 - journals.plos.org
Following the initial acute stage of spinal cord injury, a cascade of cellular and inflammatory
responses will lead to progressive secondary damage of the nerve tissue surrounding the …

Glial modulators as potential treatments of psychostimulant abuse

PM Beardsley, KF Hauser - Advances in pharmacology, 2014 - Elsevier
Glia (including astrocytes, microglia, and oligodendrocytes), which constitute the majority of
cells in the brain, have many of the same receptors as neurons, secrete neurotransmitters …