Germline risk contribution to genomic instability in multiple myeloma

S Janz, F Zhan, F Sun, Y Cheng, M Pisano… - Frontiers in …, 2019 - frontiersin.org
Genomic instability, a well-established hallmark of human cancer, is also a driving force in
the natural history of multiple myeloma (MM)–a difficult to treat and in most cases fatal …

Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma

N Thongon, F Ma, N Baran, P Lockyer, J Liu… - Nature …, 2024 - nature.com
DNA damage resistance is a major barrier to effective DNA-damaging therapy in multiple
myeloma (MM). To discover mechanisms through which MM cells overcome DNA damage …

[PDF][PDF] Multiple myeloma etiology and treatment

H Sadaf, H Hong, M Maqbool, K Emhoff… - J. Transl. Genet …, 2022 - researchgate.net
Genomic aberrations comprise hallmarks of multiple myeloma (MM), a plasma cell
malignancy with an overall poor prognosis. MM is heterogeneous and has different …