The persistent radical effect in organic synthesis
Radical–radical couplings are mostly nearly diffusion‐controlled processes. Therefore, the
selective cross‐coupling of two different radicals is challenging and not a synthetically …
selective cross‐coupling of two different radicals is challenging and not a synthetically …
C–H functionalization reactions enabled by hydrogen atom transfer to carbon-centered radicals
Selective functionalization of ubiquitous unactivated C–H bonds is a continuous quest for
synthetic organic chemists. In addition to transition metal catalysis, which typically operates …
synthetic organic chemists. In addition to transition metal catalysis, which typically operates …
Nickel and palladium catalysis: Stronger demand than ever
VM Chernyshev, VP Ananikov - Acs Catalysis, 2022 - ACS Publications
Key similarities and differences of Pd and Ni in catalytic systems are discussed. Overall, Ni
and Pd catalyze a vast number of similar C–C and C–heteroatom bond-forming reactions …
and Pd catalyze a vast number of similar C–C and C–heteroatom bond-forming reactions …
Metal-mediated and metal-catalyzed reactions under mechanochemical conditions
A Porcheddu, E Colacino, L De Luca, F Delogu - ACS Catalysis, 2020 - ACS Publications
The extraordinary impact of metal-based complexes on synthetic methods is still recognized
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
Palladium hydride-enabled hydroalkenylation of strained molecules
Z Zhang, V Gevorgyan - Journal of the American Chemical …, 2022 - ACS Publications
We report the first palladium hydride enabled hydroalkenylation of strained molecules. This
new mild protocol proceeds via a regio-and chemoselective hydropalladation step, followed …
new mild protocol proceeds via a regio-and chemoselective hydropalladation step, followed …
Photoinduced palladium-catalyzed carbofunctionalization of conjugated dienes proceeding via radical-polar crossover scenario: 1, 2-aminoalkylation and beyond
KPS Cheung, D Kurandina, T Yata… - Journal of the American …, 2020 - ACS Publications
A photoinduced palladium-catalyzed 1, 2-carbofunctionalization of conjugated dienes has
been developed. This mild modular approach, which does not require employment of …
been developed. This mild modular approach, which does not require employment of …
Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
GS Lee, D Kim, SH Hong - Nature Communications, 2021 - nature.com
The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an
unsolved problem despite their significant potential for synthetic utility and applicability. The …
unsolved problem despite their significant potential for synthetic utility and applicability. The …
Asymmetric photocatalysis enabled by chiral organocatalysts
Visible‐light photocatalysis has advanced as a versatile tool in organic synthesis. However,
attaining precise stereocontrol in photocatalytic reactions has been a longstanding …
attaining precise stereocontrol in photocatalytic reactions has been a longstanding …
Excited-state palladium-catalyzed radical migratory mizoroki–heck reaction enables C2-alkenylation of carbohydrates
Excited-state palladium catalysis has emerged as a promising strategy for developing novel
and valuable reactions. Herein, we report the first excited-state Pd-catalyzed 1, 2-radical …
and valuable reactions. Herein, we report the first excited-state Pd-catalyzed 1, 2-radical …
Excited-state palladium-catalyzed 1, 2-spin-center shift enables selective C-2 reduction, deuteration, and iodination of carbohydrates
Excited-state catalysis, a process that involves one or more excited catalytic species, has
emerged as a powerful tool in organic synthesis because it allows access to the excited …
emerged as a powerful tool in organic synthesis because it allows access to the excited …