Over the past few years, the field of regulated cell death continues to expand and novel
mechanisms that orchestrate multiple regulated cell death pathways are being unveiled …

Tuberculosis (TB), which is primarily caused by the major etiologic agent Mycobacterium
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort …

Although reactivation and accumulation of autoreactive CD4+ T cells within the CNS are
considered to play a key role in the pathogenesis of multiple sclerosis (MS) and its animal …

Objectives We previously identified a hypomorphic variant, p. Arg90His (p. R90H) of
neutrophil cytosolic factor 1 (NCF1, a regulatory subunit of phagocyte nicotinamide adenine …

Tuberculosis (TB) is a serious infectious disease caused by the pathogen Mycobacterium
tuberculosis (Mtb). The current therapy consists of a combination of antibiotics over the …

STUDY QUESTION Do human granulosa cells (GCs) ingest and destroy apoptotic oocytes?
SUMMARY ANSWER Somatic GCs ingest and destroy apoptotic oocytes and other …

Mitochondria are maternally inherited, but the mechanisms underlying paternal
mitochondrial elimination after fertilization are far less clear. Using Drosophila, we show that …

Timely and efficient elimination of apoptotic substrates, continuously produced during one's
lifespan, is a vital need for all tissues of the body. This task is achieved by cells endowed …

Objective Recent evidence from genetic, cell biology, and animal model studies has
suggested a pivotal role of autophagy in mediating systemic lupus erythematosus (SLE) …

Since molecular genotyping has been established for the Candida species, studies have
found that a single Candida strain (endemic strain) can persist over a long period of time …