Formulation and quality control of orally disintegrating tablets (ODTs): recent advances and perspectives

MP Ghourichay, SH Kiaie, A Nokhodchi… - BioMed Research …, 2021 - Wiley Online Library
Orally disintegrating tablets (ODTs) rapidly disintegrate or dissolve in the oral cavity without
using water. Demand for ODTs has increased, and the field has overgrown in the …

A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing

MS Arshad, S Zafar, B Yousef, Y Alyassin, R Ali… - Advanced drug delivery …, 2021 - Elsevier
Tablets are the most widely utilized solid oral dosage forms because of the advantages of
self-administration, stability, ease of handling, transportation, and good patient compliance …

Pediatric-friendly chocolate-based dosage forms for the oral administration of both hydrophilic and lipophilic drugs fabricated with extrusion-based 3D printing

C Karavasili, A Gkaragkounis, T Moschakis… - European Journal of …, 2020 - Elsevier
The aim of the current study was the development of pediatric-friendly 3D printed chocolate-
based oral dosage forms. Corn syrup was used to both facilitate the incorporation of a …

[HTML][HTML] Opportunities and challenges of three-dimensional printing technology in pharmaceutical formulation development

M Cui, H Pan, Y Su, D Fang, S Qiao, P Ding… - … Pharmaceutica Sinica B, 2021 - Elsevier
Three-dimensional printing is a technology that prints the products layer-by-layer, in which
materials are deposited according to the digital model designed by computer aided design …

Pharmacological effects and clinical prospects of cepharanthine

D Liang, Q Li, L Du, G Dou - Molecules, 2022 - mdpi.com
Cepharanthine is an active ingredient separated and extracted from Stephania cepharantha
Hayata, a Menispermaceae plant. As a bisbenzylisoquinoline alkaloid, cepharanthine has …

[HTML][HTML] Advances in formulation and manufacturing strategies for the delivery of therapeutic proteins and peptides in orally disintegrating dosage forms

S Bashir, R Fitaihi, HE Abdelhakim - European Journal of Pharmaceutical …, 2023 - Elsevier
Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug
molecules due to their high specificity to the site of action and reduced adverse effects …

[HTML][HTML] Orally disintegrating drug carriers for paediatric pharmacotherapy

EA Kean, OA Adeleke - European Journal of Pharmaceutical Sciences, 2023 - Elsevier
Non-compliance, dosing inaccuracy, choking risk, flavour, and instability, are some of the
issues associated with paediatric, oral dosage forms—tablets, capsules, solutions, and …

Formulation and characterisation of carbamazepine orodispersible 3D-printed mini-tablets for paediatric use

J Hu, R Fitaihi, S Abukhamees, HE Abdelhakim - Pharmaceutics, 2023 - mdpi.com
One of the main challenges to paediatric drug administration is swallowing difficulties,
hindering the acceptability of the medicine and hence clinical outcomes. This study aims at …

Meeting challenges of pediatric drug delivery: the potential of orally fast disintegrating tablets for infants and children

K Golhen, M Buettcher, J Kost, J Huwyler, M Pfister - Pharmaceutics, 2023 - mdpi.com
A majority of therapeutics are not available as suitable dosage forms for administration to
pediatric patients. The first part of this review provides an overview of clinical and …

Current status of supersaturable self-emulsifying drug delivery systems

H Park, ES Ha, MS Kim - Pharmaceutics, 2020 - mdpi.com
Self-emulsifying drug delivery systems (SEDDSs) are a vital strategy to enhance the
bioavailability (BA) of formulations of poorly water-soluble compounds. However, these …