Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

A systematic review on nanoencapsulation of food bioactive ingredients and nutraceuticals by various nanocarriers

E Assadpour, S Mahdi Jafari - Critical reviews in food science and …, 2019 - Taylor & Francis
Today, there is an ever-growing interest on natural food ingredients both by consumers and
producers in the food industry. In fact, people are looking for those products in the market …

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of Controlled Release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

Precision drug delivery to the central nervous system using engineered nanoparticles

J Gao, Z Xia, S Gunasekar, C Jiang, JM Karp… - Nature Reviews …, 2024 - nature.com
Abstract Development of novel therapies for central nervous system (CNS) disorders has
experienced a high failure rate in clinical trials owing to unsatisfactory efficacy and adverse …

Lipid nanoparticle-mediated drug delivery to the brain

P Khare, SX Edgecomb, CM Hamadani… - Advanced Drug Delivery …, 2023 - Elsevier
Lipid nanoparticles (LNPs) have revolutionized the field of drug delivery through their
applications in siRNA delivery to the liver (Onpattro) and their use in the Pfizer-BioNTech …

Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals

DJ McClements - Biotechnology advances, 2020 - Elsevier
Application of bioactive phytochemicals in foods, supplements, and pharmaceuticals is often
limited because of their poor solubility, stability, and bioavailability. Phytochemical oral …

Resveratrol‐loaded nanomedicines for cancer applications

M Annaji, I Poudel, SHS Boddu, RD Arnold… - Cancer …, 2021 - Wiley Online Library
Abstract Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and
phytoalexin, has drawn considerable attention in the past decade due to its wide variety of …

Anti-inflammatory activity of natural stilbenoids: A review

M Dvorakova, P Landa - Pharmacological Research, 2017 - Elsevier
Resveratrol and other natural stilbenoids, including piceatannol, pterostilbene, and gnetol,
are well-known anti-inflammatory compounds with indisputable activity in vitro as well as in …