[HTML][HTML] Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine
MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
Chemical and biophysical signatures of the protein corona in nanomedicine
J Ren, N Andrikopoulos, K Velonia… - Journal of the …, 2022 - ACS Publications
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
The protein corona and its effects on nanoparticle-based drug delivery systems
H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta Biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …
[HTML][HTML] Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein AI in corona formation
M Li, X Jin, T Liu, F Fan, F Gao, S Chai… - Nature communications, 2022 - nature.com
Nanoparticle elasticity is crucial in nanoparticles' physiological fate, but how this occurs is
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
[HTML][HTML] Overcoming the obstacles of current photodynamic therapy in tumors using nanoparticles
Photodynamic therapy (PDT) has been applied in clinical treatment of tumors for a long time.
However, insufficient supply of pivotal factors including photosensitizer (PS), light, and …
However, insufficient supply of pivotal factors including photosensitizer (PS), light, and …
Influence of surface chemistry and morphology of nanoparticles on protein corona formation
R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …
response to the demand for better therapeutics and diagnostics. However, the limited …
Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
[HTML][HTML] Super-stable cyanine@ albumin fluorophore for enhanced NIR-II bioimaging
Abstract Near-infrared-II (NIR-II) dyes could be encapsulated by either exogenous or
endogenous albumin to form stable complexes for deep tissue bioimaging. However, we still …
endogenous albumin to form stable complexes for deep tissue bioimaging. However, we still …
Engineering self-assembling protein nanoparticles for therapeutic delivery
A Olshefsky, C Richardson, SH Pun… - Bioconjugate …, 2022 - ACS Publications
Despite remarkable advances over the past several decades, many therapeutic
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …