Current clinical applications of diffusion-tensor imaging in neurological disorders
Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the
structure of white matter. The signal contrast in DTI is generated by differences in the …
structure of white matter. The signal contrast in DTI is generated by differences in the …
Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders
The visual system offers unparalleled precision in the assessment of neuroaxonal damage.
With the majority of patients with multiple sclerosis (MS) experiencing afferent and efferent …
With the majority of patients with multiple sclerosis (MS) experiencing afferent and efferent …
Visual evoked potentials as a biomarker in multiple sclerosis and associated optic neuritis
L Leocani, S Guerrieri, G Comi - Journal of Neuro-Ophthalmology, 2018 - journals.lww.com
Abstract From the Section Editor: The next two installments in the JNO “Disease of the Year:
Multiple Sclerosis” series focus on lessons that can be learned form the afferent visual …
Multiple Sclerosis” series focus on lessons that can be learned form the afferent visual …
[HTML][HTML] Fibre-specific white matter changes in multiple sclerosis patients with optic neuritis
S Gajamange, D Raffelt, T Dhollander, E Lui… - NeuroImage: Clinical, 2018 - Elsevier
Long term irreversible disability in multiple sclerosis (MS) is thought to be primarily driven by
axonal degeneration. Axonal degeneration leads to degenerative atrophy, therefore early …
axonal degeneration. Axonal degeneration leads to degenerative atrophy, therefore early …
Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis
ABSTRACT Introduction: Multiple Sclerosis (MS) is the most common chronic autoimmune
neuroinflammatory condition in young adults. It is often accompanied by optic neuritis (ON) …
neuroinflammatory condition in young adults. It is often accompanied by optic neuritis (ON) …
Axonal degeneration in multiple sclerosis: can we predict and prevent permanent disability?
JY Lee, K Taghian, S Petratos - Acta neuropathologica communications, 2014 - Springer
Axonal degeneration is a major determinant of permanent neurological impairment during
multiple sclerosis (MS). Due to the variable course of clinical disease and the heterogeneity …
multiple sclerosis (MS). Due to the variable course of clinical disease and the heterogeneity …
Multifocal visual evoked potentials in optic neuritis and multiple sclerosis: a review
G Pihl-Jensen, MF Schmidt, JL Frederiksen - Clinical Neurophysiology, 2017 - Elsevier
Multifocal visual evoked potential (mf-VEP) represents a new approach to the classical full
field (ff-) VEP with separate responses from up to 60 sectors of the visual field. A thorough …
field (ff-) VEP with separate responses from up to 60 sectors of the visual field. A thorough …
Sequential phases of RGC axonal and somatic injury in EAE mice examined using DTI and OCT
C Nishioka, HF Liang, B Barsamian, SW Sun - Multiple sclerosis and …, 2019 - Elsevier
Background Clinical imaging modalities including optical coherence tomography (OCT) and
diffusion tensor imaging (DTI) are vital in Multiple Sclerosis (MS), but their relationships …
diffusion tensor imaging (DTI) are vital in Multiple Sclerosis (MS), but their relationships …
Amyloid-beta induced retrograde axonal degeneration in a mouse tauopathy model
C Nishioka, HF Liang, B Barsamian, SW Sun - Neuroimage, 2019 - Elsevier
White matter abnormalities, revealed by Diffusion Tensor Imaging (DTI), are observed in
patients with Alzheimer's Disease (AD), representing neural network deficits that underlie …
patients with Alzheimer's Disease (AD), representing neural network deficits that underlie …
Diffuse and focal corticospinal tract disease and its impact on patient disability in multiple sclerosis
F Tovar‐Moll, IE Evangelou, AW Chiu… - Journal of …, 2015 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE We investigated the impact of focal and diffuse
corticospinal tracts damage on sensory‐motor disability in multiple sclerosis (MS) patients …
corticospinal tracts damage on sensory‐motor disability in multiple sclerosis (MS) patients …