Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories
T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
Navigating for reward
M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …
associated with rewards, such as food or a home. Accumulating research has revealed that …
The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation
HR Joo, LM Frank - Nature Reviews Neuroscience, 2018 - nature.com
Various cognitive functions have long been known to require the hippocampus. Recently,
progress has been made in identifying the hippocampal neural activity patterns that …
progress has been made in identifying the hippocampal neural activity patterns that …
Alternating sequences of future and past behavior encoded within hippocampal theta oscillations
M Wang, DJ Foster, BE Pfeiffer - Science, 2020 - science.org
Neural networks display the ability to transform forward-ordered activity patterns into reverse-
ordered, retrospective sequences. The mechanisms underlying this transformation remain …
ordered, retrospective sequences. The mechanisms underlying this transformation remain …
[HTML][HTML] A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations
Decades of rodent research have established the role of hippocampal sharp wave ripples
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …
Assessments of dentate gyrus function: discoveries and debates
There has been considerable speculation regarding the function of the dentate gyrus (DG)—
a subregion of the mammalian hippocampus—in learning and memory. In this Perspective …
a subregion of the mammalian hippocampus—in learning and memory. In this Perspective …
[HTML][HTML] Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice
Previous work has shown that motor skill learning stimulates and requires generation of
myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult …
myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult …
[PDF][PDF] Assembly responses of hippocampal CA1 place cells predict learned behavior in goal-directed spatial tasks on the radial eight-arm maze
Hippocampus is needed for both spatial working and reference memories. Here, using a
radial eight-arm maze, we examined how the combined demand on these memories …
radial eight-arm maze, we examined how the combined demand on these memories …
[PDF][PDF] On how the dentate gyrus contributes to memory discrimination
MT van Dijk, AA Fenton - Neuron, 2018 - cell.com
The dentate gyrus (DG) is crucial for behaviorally discriminating similar spatial memories,
predicting that DG place cells change (" remap") their relative spatial tuning (" place fields") …
predicting that DG place cells change (" remap") their relative spatial tuning (" place fields") …
Contributions of adult neurogenesis to dentate gyrus network activity and computations
SN Tuncdemir, CO Lacefield, R Hen - Behavioural Brain Research, 2019 - Elsevier
Anatomical observations, theoretical work and lesion experiments have led to the idea that
an important function of the dentate gyrus of the mammalian hippocampus is pattern …
an important function of the dentate gyrus of the mammalian hippocampus is pattern …