Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

Navigating for reward

M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation

HR Joo, LM Frank - Nature Reviews Neuroscience, 2018 - nature.com
Various cognitive functions have long been known to require the hippocampus. Recently,
progress has been made in identifying the hippocampal neural activity patterns that …

Alternating sequences of future and past behavior encoded within hippocampal theta oscillations

M Wang, DJ Foster, BE Pfeiffer - Science, 2020 - science.org
Neural networks display the ability to transform forward-ordered activity patterns into reverse-
ordered, retrospective sequences. The mechanisms underlying this transformation remain …

[HTML][HTML] A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

AA Liu, S Henin, S Abbaspoor, A Bragin… - Nature …, 2022 - nature.com
Decades of rodent research have established the role of hippocampal sharp wave ripples
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …

Assessments of dentate gyrus function: discoveries and debates

M Borzello, S Ramirez, A Treves, I Lee… - Nature Reviews …, 2023 - nature.com
There has been considerable speculation regarding the function of the dentate gyrus (DG)—
a subregion of the mammalian hippocampus—in learning and memory. In this Perspective …

[HTML][HTML] Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice

T Shimizu, SG Nayar, M Swire, Y Jiang, M Grist… - Nature …, 2023 - nature.com
Previous work has shown that motor skill learning stimulates and requires generation of
myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult …

[PDF][PDF] Assembly responses of hippocampal CA1 place cells predict learned behavior in goal-directed spatial tasks on the radial eight-arm maze

H Xu, P Baracskay, J O'Neill, J Csicsvari - Neuron, 2019 - cell.com
Hippocampus is needed for both spatial working and reference memories. Here, using a
radial eight-arm maze, we examined how the combined demand on these memories …

[PDF][PDF] On how the dentate gyrus contributes to memory discrimination

MT van Dijk, AA Fenton - Neuron, 2018 - cell.com
The dentate gyrus (DG) is crucial for behaviorally discriminating similar spatial memories,
predicting that DG place cells change (" remap") their relative spatial tuning (" place fields") …

Contributions of adult neurogenesis to dentate gyrus network activity and computations

SN Tuncdemir, CO Lacefield, R Hen - Behavioural Brain Research, 2019 - Elsevier
Anatomical observations, theoretical work and lesion experiments have led to the idea that
an important function of the dentate gyrus of the mammalian hippocampus is pattern …