Application of proteomics in cancer: recent trends and approaches for biomarkers discovery

YW Kwon, HS Jo, S Bae, Y Seo, P Song, M Song… - Frontiers in …, 2021 - frontiersin.org
Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …

Saliva proteomics updates in biomedicine

KR Katsani, D Sakellari - Journal of Biological Research-Thessaloniki, 2019 - Springer
In the years of personalized (or precision) medicine the 'omics' methodologies in biomedical
sciences—genomics, transcriptomics, proteomics and metabolomics—are helping …

Evaluation of sample preparation methods for fast proteotyping of microorganisms by tandem mass spectrometry

K Hayoun, D Gouveia, L Grenga, O Pible… - Frontiers in …, 2019 - frontiersin.org
Tandem mass spectrometry-based proteotyping allows characterizing microorganisms in
terms of taxonomy and is becoming an important tool for investigating microbial diversity …

The human salivary proteome wiki: a community-driven research platform

WW Lau, M Hardt, YH Zhang… - Journal of Dental …, 2021 - journals.sagepub.com
Saliva has become an attractive body fluid for on-site, remote, and real-time monitoring of
oral and systemic health. At the same time, the scientific community needs a saliva-centered …

Oral microbial species and virulence factors associated with oral squamous cell carcinoma

MG Torralba, G Aleti, W Li, KJ Moncera, YH Lin, Y Yu… - Microbial ecology, 2021 - Springer
The human microbiome has been the focus of numerous research efforts to elucidate the
pathogenesis of human diseases including cancer. Oral cancer mortality is high when …

SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling

B Zhao, W Gong, A Ma, J Chen, M Velegraki… - Nature …, 2022 - nature.com
Dysfunctional CD8+ T cells, which have defective production of antitumor effectors,
represent a major mediator of immunosuppression in the tumor microenvironment. Here, we …

Kinetic multi-omic analysis of responses to SARS-CoV-2 infection in a model of severe COVID-19

AM Cantwell, H Singh, M Platt, Y Yu, YH Lin… - Journal of …, 2021 - Am Soc Microbiol
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
poorly understood due to a lack of an animal model that recapitulates severe human …

Optimized suspension trapping method for phosphoproteomics sample preparation

F Wang, T Veth, M Kuipers, M Altelaar… - Analytical …, 2023 - ACS Publications
A successful mass spectrometry-based phosphoproteomics analysis relies on effective
sample preparation strategies. Suspension trapping (S-Trap) is a novel, rapid, and universal …

Global proteome and phosphoproteome characterization of sepsis-induced kidney injury

YH Lin, MP Platt, H Fu, Y Gui, Y Wang… - Molecular & Cellular …, 2020 - ASBMB
Sepsis-induced acute kidney injury (S-AKI) is the most common complication in hospitalized
and critically ill patients, highlighted by a rapid decline of kidney function occurring a few …

A multiomics analysis of direct interkingdom dynamics between influenza A virus and Streptococcus pneumoniae uncovers host-independent changes to bacterial …

MP Platt, YH Lin, T Penix, R Wiscovitch-Russo… - Plos …, 2022 - journals.plos.org
Background For almost a century, it has been recognized that influenza A virus (IAV)
infection can promote the development of secondary bacterial infections (SBI) mainly …