Autophagy as an emerging target in cardiorenal metabolic disease: from pathophysiology to management

Y Zhang, AT Whaley-Connell, JR Sowers… - Pharmacology & …, 2018 - Elsevier
Although advances in medical technology and health care have improved the early
diagnosis and management for cardiorenal metabolic disorders, the prevalence of obesity …

MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy

K Ait-Aissa, QM Nguyen, M Gabani, A Kassan… - Cardiovascular …, 2020 - Springer
The endothelium plays a pivotal role in maintaining vascular health. Obesity is a global
epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity …

A high resolution atlas of gene expression in the domestic sheep (Ovis aries)

EL Clark, SJ Bush, MEB McCulloch, IL Farquhar… - PLoS …, 2017 - journals.plos.org
Sheep are a key source of meat, milk and fibre for the global livestock sector, and an
important biomedical model. Global analysis of gene expression across multiple tissues has …

miRNA and mRNA expression analysis reveals potential sex-biased miRNA expression

L Guo, Q Zhang, X Ma, J Wang, T Liang - Scientific reports, 2017 - nature.com
Recent studies suggest that mRNAs may be differentially expressed between males and
females. This study aimed to perform expression analysis of mRNA and its main regulatory …

The effects of a mixture of cadmium, lead, and mercury on metabolic syndrome and its components, as well as cognitive impairment: genes, MicroRNAs, transcription …

HD Nguyen, MS Kim - Biological Trace Element Research, 2023 - Springer
Converging evidence indicates heavy metal–induced genes, transcription factors (TFs), and
microRNAs (miRNAs) are critical pathological components of metabolic syndrome (MetS) …

Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR-24-3p/Igf2/PI3K-AKT-mTOR and Igf2bp2/Ucp1 axis

J Shao, M Wang, A Zhang, Z Liu, G Jiang… - Cellular and Molecular …, 2023 - Springer
White adipose tissue (WAT) is important for regulating the whole systemic energy
homeostasis. Excessive WAT accumulation further contributes to the development of obesity …

The expression profile and role of non-coding RNAs in obesity

S Ghafouri-Fard, M Taheri - European Journal of Pharmacology, 2021 - Elsevier
Latest years have experienced a dramatic upsurge in the knowledge about the function of
non-coding transcripts in the determination of diverse human phenotypes including obesity …

Emerging roles of non-coding RNAs in the feed efficiency of livestock species

G Hu, DN Do, P Davoudi, Y Miar - Genes, 2022 - mdpi.com
A global population of already more than seven billion people has led to an increased
demand for food and water, and especially the demand for meat. Moreover, the cost of feed …

Hepatic galectin-3 is associated with lipid droplet area in non-alcoholic steatohepatitis in a new swine model

LV Herrera-Marcos, R Martínez-Beamonte… - Scientific Reports, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is currently a growing epidemic disease that can
lead to cirrhosis and hepatic cancer when it evolves into non-alcoholic steatohepatitis …

MicroRNAs as potential regulators of glutathione peroxidases expression and their role in obesity and related pathologies

P Matoušková, B Hanousková, L Skálová - International Journal of …, 2018 - mdpi.com
Glutathione peroxidases (GPxs) belong to the eight-member family of phylogenetically
related enzymes with different cellular localization, but distinct antioxidant function. Several …