α-Synuclein is a protein with a molecular weight of 14.5 kDa and consists of 140 amino
acids encoded by the SNCA gene. Missense mutations and gene duplications in the SNCA …

Biomolecules | Free Full-Text | Alpha-Synuclein and the Endolysosomal System in Parkinson’s
Disease: Guilty by Association Next Article in Journal HMGA1, Moonlighting Protein Function …

Rationale: Glioblastoma (GBM) is the most common and malignant primary brain tumor in
adults. Radiotherapy has long been an important treatment for GBM. Despite recent …

Flotillin-1 and flotillin-2 are ubiquitously expressed, membrane-associated proteins involved
in multifarious cellular events from cell signaling, endocytosis, and protein trafficking to gene …

FLOT1, a scaffold protein of lipid rafts, is involved in several biological processes, including
lipid raft protein‑dependent or clathrin‑independent endocytosis, and the formation of …

Nigrostriatal dopaminergic systems govern physiological functions related to locomotion,
and their dysfunction leads to movement disorders, such as Parkinson's disease and dopa …

As extracellular vesicles, exosomes are released from most cells to perform cell–cell
communication. Recent studies have shown that exosomes could be released into tumor …

Endocytosis is the fundamental uptake process through which cells internalize extracellular
materials and species. Neurodegenerative diseases (NDs) are characterized by a …

Since its discovery 30 years ago, α-synuclein (α-syn) has been one of the most studied
proteins in the field of neuroscience. Dozens of groups worldwide have tried to reveal not …

Abstract “Path to a good mood lies through the gut.” This statement seems to imply that it has
long been believed that the gut is connected with the brain. Research has shown that eating …