The mammalian blood-testis barrier: its biology and regulation

DD Mruk, CY Cheng - Endocrine reviews, 2015 - academic.oup.com
Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

The blood-testis barrier and its implications for male contraception

CY Cheng, DD Mruk - Pharmacological reviews, 2012 - ASPET
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

Molecular insights into transgenerational non-genetic inheritance of acquired behaviours

J Bohacek, IM Mansuy - Nature Reviews Genetics, 2015 - nature.com
Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …

Autophagy: a multifaceted player in the fate of sperm

M Wang, L Zeng, P Su, L Ma, M Zhang… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Autophagy is an intracellular catabolic process of degrading and recycling
proteins and organelles to modulate various physiological and pathological events …

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

LT Gou, P Dai, JH Yang, Y Xue, YP Hu, Y Zhou… - Cell research, 2014 - nature.com
Spermatogenesis in mammals is characterized by two waves of piRNA expression: one
corresponds to classic piRNAs responsible for silencing retrotransponsons and the second …

Spermatogenesis in fish

RW Schulz, LR de França, JJ Lareyre, F LeGac… - General and …, 2010 - Elsevier
Spermatogenesis is a developmental process during which a small number of diploid
spermatogonial stem cells produce a large number of highly differentiated spermatozoa …

Diverse monogenic subforms of human spermatogenic failure

L Nagirnaja, AM Lopes, WL Charng, B Miller… - Nature …, 2022 - nature.com
Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically
incurable. Defining the genetic basis of NOA has proven challenging, and the most …

Essential role of histone replacement and modifications in male fertility

T Wang, H Gao, W Li, C Liu - Frontiers in genetics, 2019 - frontiersin.org
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …

Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis

SS Hammoud, DHP Low, C Yi, DT Carrell, E Guccione… - Cell stem cell, 2014 - cell.com
Adult germline stem cells (AGSCs) self-renew (Thy1+ enriched) or commit to gametogenesis
(Kit+ enriched). To better understand how chromatin regulates AGSC biology and …

Calcium channels in the development, maturation, and function of spermatozoa

A Darszon, T Nishigaki, C Beltran… - Physiological …, 2011 - journals.physiology.org
A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …