The mammalian blood-testis barrier: its biology and regulation
DD Mruk, CY Cheng - Endocrine reviews, 2015 - academic.oup.com
Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
The blood-testis barrier and its implications for male contraception
CY Cheng, DD Mruk - Pharmacological reviews, 2012 - ASPET
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
Molecular insights into transgenerational non-genetic inheritance of acquired behaviours
Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …
with the genome and modulate its activity by complex molecular interplay. Environmental …
Autophagy: a multifaceted player in the fate of sperm
M Wang, L Zeng, P Su, L Ma, M Zhang… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Autophagy is an intracellular catabolic process of degrading and recycling
proteins and organelles to modulate various physiological and pathological events …
proteins and organelles to modulate various physiological and pathological events …
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis
Spermatogenesis in mammals is characterized by two waves of piRNA expression: one
corresponds to classic piRNAs responsible for silencing retrotransponsons and the second …
corresponds to classic piRNAs responsible for silencing retrotransponsons and the second …
Spermatogenesis in fish
Spermatogenesis is a developmental process during which a small number of diploid
spermatogonial stem cells produce a large number of highly differentiated spermatozoa …
spermatogonial stem cells produce a large number of highly differentiated spermatozoa …
Diverse monogenic subforms of human spermatogenic failure
L Nagirnaja, AM Lopes, WL Charng, B Miller… - Nature …, 2022 - nature.com
Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically
incurable. Defining the genetic basis of NOA has proven challenging, and the most …
incurable. Defining the genetic basis of NOA has proven challenging, and the most …
Essential role of histone replacement and modifications in male fertility
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …
distinct morphological change, and the protamines replace the core histones to facilitate …
Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis
Adult germline stem cells (AGSCs) self-renew (Thy1+ enriched) or commit to gametogenesis
(Kit+ enriched). To better understand how chromatin regulates AGSC biology and …
(Kit+ enriched). To better understand how chromatin regulates AGSC biology and …
Calcium channels in the development, maturation, and function of spermatozoa
A Darszon, T Nishigaki, C Beltran… - Physiological …, 2011 - journals.physiology.org
A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …