The Maillard reaction, starting from the glycation of protein and progressing to the formation
of advanced glycation end-products (AGEs), is implicated in the development of …

In medicine, there is an urgent need for protein biomarkers in a range of applications that
includes diagnostics, disease stratification, and therapeutic decisions. One of the main …

Mass spectrometry-based proteomics has become the tool of choice for identifying and
quantifying the proteome of an organism. Though recent years have seen a tremendous …

Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …

Recent advances in proteomics technologies provide tremendous opportunities for
biomarker-related clinical applications; however, the distinctive characteristics of human …

Serum is an ideal biological sample that contains an archive of information due to the
presence of a variety of proteins released by diseased tissue, and serum proteomics has …

The enormous dynamic range of human bodily fluid proteomes poses a significant
challenge for current MS-based proteomics technologies as it makes it especially difficult to …

Over the past decades, substantial advances have been made in both the early diagnosis
and accurate prognosis of many cancers because of the impressive development of novel …

Sepsis is a complex syndrome promoted by pathogenic and host factors; it is characterized
by dysregulated host responses and multiple organ dysfunction, which can lead to death …

The field of clinical proteomics offers opportunities to identify new disease biomarkers in
body fluids, cells and tissues. These biomarkers can be used in clinical applications for …